Protein: RAB6B
Ras-related protein Rab-6B (EC 3.6.5.2)

Gene: RAB6B
Organism: Homo sapiens
Interactions: 115
UniProt ID: Q9NRW1

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005654 - nucleoplasm
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

724523

GDIA
Rab GDP dissociation inhibitor alpha

4

20

High-throughput

0.900

High

631702

RAB6A
Ras-related protein Rab-6A

4

18

High-throughput

0.892

High

1034069

OCRL
Inositol polyphosphate 5-phosphatase OCRL

4

17

High-throughput

0.892

High

911878

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

4

3

High-throughput

0.890

High

894600

GDIB
Rab GDP dissociation inhibitor beta

3

20

High-throughput

0.871

High

789027

TGFR2
TGF-beta receptor type-2

3

10

High-throughput

0.861

High

331808

MTMR5
Myotubularin-related protein 5

3

11

High-throughput

0.855

High

664906

RAE1
Rab proteins geranylgeranyltransferase component A 1

3

20

High-throughput

0.855

High

686595

RAE2
Rab proteins geranylgeranyltransferase component A 2

3

20

High-throughput

0.855

High

1206595

RAB41
Ras-related protein Rab-41

2

18

High-throughput

0.811

High

1430241

RAB6C
Ras-related protein Rab-6C

2

19

High-throughput

0.811

High

154442

SH2B2
SH2B adapter protein 2

2

15

High-throughput

0.783

High

631500

RAB5A
Ras-related protein Rab-5A

2

19

High-throughput

0.737

High

1036691

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

15

Small-scale

0.713

High

1116043

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

11

High-throughput

0.691

High

1429556

RB33B
Ras-related protein Rab-33B

1

19

High-throughput

0.691

High

1448888

COG6
Conserved oligomeric Golgi complex subunit 6

3

3

High-throughput

0.671

High

1448880

KTU
Protein kintoun

3

3

High-throughput

0.667

High

1448884

NUFP1
FMR1-interacting protein NUFIP1

3

1

High-throughput

0.667

High

921573

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

4

High-throughput

0.662

High

1112392

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

3

4

High-throughput

0.662

High

1366814

PGTA
Geranylgeranyl transferase type-2 subunit alpha

3

17

High-throughput

0.662

High

1325765

LNX2
Ligand of Numb protein X 2

1

8

High-throughput

0.647

High

1307207

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

16

Small-scale

0.647

High

1141481

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

2

5

High-throughput

0.628

High

1217918

BRE1A
E3 ubiquitin-protein ligase BRE1A

2

9

High-throughput

0.628

High

1310797

CUL9
Cullin-9

2

8

High-throughput

0.628

High

1338636

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

2

5

High-throughput

0.628

High

1340747

TPC2
Two pore channel protein 2

2

7

High-throughput

0.628

High

1448885

S12A6
Solute carrier family 12 member 6

4

20

Small-scale

0.619

High

1116844

AVR2B
Activin receptor type-2B

1

10

High-throughput

0.618

High

1438486

RXFP1
Relaxin receptor 1

1

3

High-throughput

0.618

High

630990

RAB4A
Ras-related protein Rab-4A

1

18

High-throughput

0.618

High

1400340

FMNL2
Formin-like protein 2

1

9

High-throughput

0.618

High

124511

HAX1
HCLS1-associated protein X-1

3

3

High-throughput

0.609

High

1350465

BICD2
Protein bicaudal D homolog 2

2

14

High-throughput

0.606

High

1369654

PMM1
Phosphomannomutase 1

2

2

High-throughput

0.606

High

1448887

S12A4
Solute carrier family 12 member 4

3

20

High-throughput

0.587

High

1288927

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

9

High-throughput

0.575

High

1387194

RB39B
Ras-related protein Rab-39B

1

19

High-throughput

0.575

High

1439563

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

6

High-throughput

0.575

High

1103850

TARB1
tRNA

2

1

High-throughput

0.574

High

1156952

CNGA3
Cyclic nucleotide-gated channel alpha-3

2

7

High-throughput

0.574

High

1448891

PCDC2
Protocadherin alpha-C2

2

3

High-throughput

0.574

High

397027

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

1433993

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

944861

PCBP3
Poly(rC)-binding protein 3

1

1

High-throughput

0.536

High

1055864

RING1
E3 ubiquitin-protein ligase RING1

1

7

High-throughput

0.536

High

1281234

VP13B
Intermembrane lipid transfer protein VPS13B

1

20

High-throughput

0.536

High

1448881

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

3

High-throughput

0.536

High

906934

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

1448883

SHPK
Sedoheptulokinase

1

0

High-throughput

0.513

High

213700

AQP9
Aquaporin-9

1

7

High-throughput

0.489

High

956112

SPCS3
Signal peptidase complex subunit 3

1

1

High-throughput

0.489

High

1251996

TM11A
Transmembrane protease serine 11A

1

7

High-throughput

0.489

High

1278123

MAVS
Mitochondrial antiviral-signaling protein

1

6

High-throughput

0.489

High

1396545

CALR3
Calreticulin-3

1

6

High-throughput

0.489

High

1448882

EGFL7
Epidermal growth factor-like protein 7

1

5

High-throughput

0.489

High

1448886

PCDAC
Protocadherin alpha-12

1

3

High-throughput

0.489

High

1448889

PCDGH
Protocadherin gamma-B5

1

3

High-throughput

0.489

High

1448890

PCDGE
Protocadherin gamma-B2

1

3

High-throughput

0.489

High

331354

KI20A
Kinesin-like protein KIF20A

1

14

Small-scale

0.481

High

243049

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

325124

HEXI1
Protein HEXIM1

1

7

High-throughput

0.479

High

373250

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

537971

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

589800

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

623562

RO52
E3 ubiquitin-protein ligase TRIM21

1

7

High-throughput

0.479

High

696616

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

11

High-throughput

0.479

High

769282

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

851676

GATA4
Transcription factor GATA-4

1

1

High-throughput

0.479

High

856942

BAG6
Large proline-rich protein BAG6

1

10

Small-scale

0.479

High

879504

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

904146

BAP31
B-cell receptor-associated protein 31

1

6

Small-scale

0.479

High

913813

ZN131
Zinc finger protein 131

1

1

High-throughput

0.479

High

947286

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

2

High-throughput

0.479

High

987970

GRB2
Growth factor receptor-bound protein 2

1

17

High-throughput

0.479

High

1008903

RED1
Double-stranded RNA-specific editase 1

1

3

High-throughput

0.479

High

1334583

RN149
E3 ubiquitin-protein ligase RNF149

1

19

High-throughput

0.479

High

1366584

AKAP1
A-kinase anchor protein 1, mitochondrial

1

12

High-throughput

0.479

High

1420365

TRI31
E3 ubiquitin-protein ligase TRIM31

1

19

High-throughput

0.479

High

1420947

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

1436329

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1232598

Q6FHY5
MEOX2 protein

1

6

High-throughput

0.470

High

1047490

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.458

High

1085625

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1164237

DGUOK
Deoxyguanosine kinase, mitochondrial

1

0

High-throughput

0.458

High

342464

RPP29
Ribonuclease P protein subunit p29

1

1

High-throughput

0.445

High

471933

RU2B
U2 small nuclear ribonucleoprotein B''

1

7

High-throughput

0.445

High

530431

TAU
Microtubule-associated protein tau

1

17

High-throughput

0.445

High

574486

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.445

High

935175

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.445

High

954416

SNP25
Synaptosomal-associated protein 25

1

9

Small-scale

0.445

High

1119325

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1431172

S35B3
Adenosine 3'-phospho 5'-phosphosulfate transporter 2

1

6

High-throughput

0.445

High

894192

MEOX2
Homeobox protein MOX-2

1

6

High-throughput

0.439

High

106707

APRIO
Alternative prion protein

1

7

High-throughput

0.437

High

294388

CD123
Translation initiation factor eIF2 assembly protein

1

6

High-throughput

0.437

High

1294268

GOLI
E3 ubiquitin-protein ligase RNF130

1

20

High-throughput

0.437

High

1428552

DDX24
ATP-dependent RNA helicase DDX24

1

3

High-throughput

0.437

High

404926

PRIO
Major prion protein

1

0

High-throughput

0.426

High

255232

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.407

High

538854

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

18

High-throughput

0.407

High

1417154

S12A9
Solute carrier family 12 member 9

1

20

High-throughput

0.407

High

1417777

SC11C
Signal peptidase complex catalytic subunit SEC11C

1

2

High-throughput

0.407

High

1309974

CC117
Coiled-coil domain-containing protein 117

2

0

High-throughput

0.328

High

1324276

LYPD1
Ly6/PLAUR domain-containing protein 1

2

0

High-throughput

0.328

High

1334328

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

0

High-throughput

0.328

High

248513

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.279

Low

1214133

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

1272905

VASH1
Tubulinyl-Tyr carboxypeptidase 1

1

0

High-throughput

0.279

Low

1382752

ISOC2
Isochorismatase domain-containing protein 2

1

0

High-throughput

0.279

Low

1386165

FWCH2
FLYWCH family member 2

1

0

High-throughput

0.279

Low

1012627

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.232

Low

1445806

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025