Interactor 1: Q8BNP7 (Q8BNP7)
Adenomatous polyposis coli N-terminal dimerisation domain-containing protein
Gene: Apc

Interactor 2: GSK3B (Q9WV60)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 25331900, 15327768
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0008013 - beta-catenin binding
GO:0016055 - Wnt signaling pathway
GO:0016477 - cell migration
GO:0030877 - beta-catenin destruction complex
GO:0045732 - positive regulation of protein catabolic process
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1056
Mm

1 420
+ Rn
+ Mm
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024