HitPredict

Interactor 1: CSN7B (Q8BV13)
COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b)
Gene: Cops7b

Interactor 2: CSN1 (Q99LD4)
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1)
Gene: Gps1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20974137
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PCI~PCI, PCI~RPN7
Common GO terms	GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 264 Mm			1 471
+	Mm
		102351 CSN7B_MOUSE (1-264): 5.17e-107: 312: 100.00		G3UXW9_MOUSE (1-471): 1.48e-174: 501: 100.00
+	Hs
		1024222 CSN7B_HUMAN (1-264): 3.34e-107: 312: 98.11		CSN1_HUMAN (1-471): 8.36e-170: 488: 96.84
+	Mm
		102353 CSN7A_MOUSE (1-262): 1.33e-87: 263: 57.68		G3UXW9_MOUSE (1-471): 1.48e-174: 501: 100.00
+	Hs
		1024236 CSN7A_HUMAN (1-262): 5.81e-89: 266: 58.05		CSN1_HUMAN (1-471): 8.36e-170: 488: 96.84
+	Hs
		897312 CSN7B_HUMAN (1-264): 3.34e-107: 312: 98.11		CSN2_HUMAN (6-438): 5.94e-116: 349: 14.90
+	At
		799477 CSN7_ARATH (5-220): 3.24e-77: 236: 36.41		CSN1_ARATH (9-448): 3.49e-129: 383: 44.82
+	Dm
		1277031 CSN7_DROME (1-262): 3.24e-94: 280: 43.77		CSN2_DROME (10-438): 1.39e-110: 335: 15.23
+	Hs
		897324 CSN7A_HUMAN (1-262): 5.81e-89: 266: 58.05		CSN2_HUMAN (6-438): 5.94e-116: 349: 14.90
+	Mm
		897342 CSN7A_MOUSE (1-262): 1.33e-87: 263: 57.68		CSN2_MOUSE (6-438): 5.94e-116: 349: 14.90
+	Hs
		1062898 PSD13_HUMAN (40-191): 3.86e-56: 186: 17.28		PSMD6_HUMAN (50-434): 3.13e-123: 366: 21.56
+	At
		1278364 CSN7_ARATH (5-220): 3.24e-77: 236: 36.41		PSD11_ARATH (34-442): 1.59e-95: 296: 13.24
+	Dm
		1180993 Q7KMP8_DROME (24-191): 2.96e-51: 173: 19.66		PSMD6_DROME (48-434): 2.27e-117: 351: 20.67
+	Hs
		121872 PSD13_HUMAN (40-191): 3.86e-56: 186: 17.28		PSD11_HUMAN (35-440): 1.01e-110: 335: 14.42
+	Ce
		1276131 EIF3M_CAEEL (5-216): 2.17e-46: 161: 20.46		CSN1_CAEEL (5-457): 4.66e-107: 332: 25.15
+	Dm
		1180705 Q7KMP8_DROME (24-191): 2.96e-51: 173: 19.66		PSD11_DROME (36-440): 6.36e-104: 318: 14.93
+	An
		961357 CSN7_EMENI (12-229): 2.6e-51: 172: 30.26		CSN2_EMENI (4-429): 2.59e-97: 303: 13.11
+	Ce
		136315 EIF3M_CAEEL (5-216): 2.17e-46: 161: 20.46		CSN2_CAEEL (11-413): 2.56e-98: 305: 13.70
+	Sp
		1013799 RPN9_SCHPO (25-189): 5.03e-45: 157: 17.14		RPN7_SCHPO (48-446): 4.65e-98: 302: 18.43
+	Sc
		978500 RPN9_YEAST (8-191): 7.84e-45: 157: 18.56		RPN7_YEAST (5-432): 1.25e-86: 273: 21.02
+	Sc
		978512 RPN9_YEAST (8-191): 7.84e-45: 157: 18.56		RPN6_YEAST (68-440): 3.93e-84: 267: 12.60