Interactor 1: CGAS (Q8C6L5)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (m-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS
Interactor 2: CGAS (Q8C6L5)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (m-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.647 |
The method score is based on:
Property | Details |
---|---|
Experiments | 28902841 |
Identification Methods | x-ray crystallography |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Mab-21~Mab-21, Mab-21~Mab-21_C, Mab-21_C~Mab-21_C |
Common GO terms | GO:0002218 - activation of innate immune response GO:0002230 - positive regulation of defense response to virus by host GO:0002637 - regulation of immunoglobulin production GO:0003677 - DNA binding GO:0003682 - chromatin binding and 33 others more... |
Homologous interactions | 3 |
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Last updated: 15 Jul 2024