Interactor 1: CGAS (Q8C6L5)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (m-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS

Interactor 2: CGAS (Q8C6L5)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (m-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 28902841
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Mab-21~Mab-21, Mab-21~Mab-21_C, Mab-21_C~Mab-21_C
Common GO terms GO:0002218 - activation of innate immune response
GO:0002230 - positive regulation of defense response to virus by host
GO:0002637 - regulation of immunoglobulin production
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
and 33 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 507
Mm

1 507
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024