Protein: M3K7
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)

Gene: M3K7, MAP3K7
Organism: Homo sapiens
Interactions: 394
UniProt ID: O43318

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000287 - magnesium ion binding
GO:0001223 - transcription coactivator binding
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002726 - positive regulation of T cell cytokine production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

213869

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

23

20

Small-scale

0.990

High

167771

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

20

10

Small-scale

0.988

High

213723

M3K7
Mitogen-activated protein kinase kinase kinase 7

13

18

Small-scale

0.981

High

177741

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

10

13

Small-scale

0.969

High

213940

CDC37
Hsp90 co-chaperone Cdc37

6

9

Small-scale

0.949

High

213866

IRAK1
Interleukin-1 receptor-associated kinase 1

5

20

Small-scale

0.916

High

213724

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

4

20

Small-scale

0.894

High

213926

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

4

20

Small-scale

0.881

High

213896

XIAP
E3 ubiquitin-protein ligase XIAP

3

11

Small-scale

0.871

High

213776

HS90A
Heat shock protein HSP 90-alpha

3

20

Small-scale

0.867

High

213924

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

3

7

High-throughput

0.861

High

214070

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

3

15

Small-scale

0.847

High

213919

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

3

9

Small-scale

0.834

High

213841

TGFR1
TGF-beta receptor type-1

3

19

Small-scale

0.827

High

213902

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

2

19

Small-scale

0.819

High

214007

M3K5
Mitogen-activated protein kinase kinase kinase 5

2

19

Small-scale

0.815

High

214009

M3K3
Mitogen-activated protein kinase kinase kinase 3

2

10

Small-scale

0.815

High

213845

STAT3
Signal transducer and activator of transcription 3

2

4

Small-scale

0.802

High

191193

TLR3
Toll-like receptor 3

2

20

Small-scale

0.789

High

213777

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.789

High

213795

EZRI
Ezrin

2

15

High-throughput

0.789

High

213958

VRK2
Serine/threonine-protein kinase VRK2

2

8

Small-scale

0.789

High

214032

HIPK2
Homeodomain-interacting protein kinase 2

2

20

Small-scale

0.777

High

213885

1433E
14-3-3 protein epsilon

2

6

Small-scale

0.776

High

213908

1433F
14-3-3 protein eta

2

20

High-throughput

0.776

High

214006

M3K14
Mitogen-activated protein kinase kinase kinase 14

2

15

Small-scale

0.776

High

214050

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

45

6

Small-scale

0.771

High

213938

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

39

7

Small-scale

0.771

High

214085

TRAF6
TNF receptor-associated factor 6

34

20

Small-scale

0.769

High

213856

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

2

20

Small-scale

0.768

High

213967

TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

22

6

Small-scale

0.767

High

214052

NLK
Serine/threonine-protein kinase NLK

2

15

Small-scale

0.759

High

213906

KPCT
Protein kinase C theta type

2

10

Small-scale

0.754

High

214093

NEMO
NF-kappa-B essential modulator

10

5

Small-scale

0.750

High

213855

MK08
Mitogen-activated protein kinase 8

1

17

Small-scale

0.747

High

213802

TNR1A
Tumor necrosis factor receptor superfamily member 1A

7

6

Small-scale

0.739

High

213761

TNFA
Tumor necrosis factor

7

1

Small-scale

0.735

High

213732

KERA
Keratocan

2

20

High-throughput

0.726

High

213879

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

10

Small-scale

0.724

High

213916

BIRC1
Baculoviral IAP repeat-containing protein 1

1

8

Small-scale

0.724

High

213927

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

6

Small-scale

0.724

High

214021

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

16

Small-scale

0.724

High

214059

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

Small-scale

0.715

High

213781

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

6

Small-scale

0.713

High

213914

TRAF2
TNF receptor-associated factor 2

5

20

Small-scale

0.709

High

214024

TRIM8
E3 ubiquitin-protein ligase TRIM8

4

13

Small-scale

0.692

High

214046

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

4

2

Small-scale

0.692

High

213793

ENPL
Endoplasmin

1

20

High-throughput

0.691

High

213817

MOES
Moesin

1

14

High-throughput

0.691

High

213838

RADI
Radixin

1

14

High-throughput

0.691

High

213865

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.691

High

213867

NEK4
Serine/threonine-protein kinase Nek4

1

9

High-throughput

0.691

High

213899

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

5

High-throughput

0.691

High

213904

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

7

High-throughput

0.691

High

213913

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.691

High

214071

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

5

High-throughput

0.691

High

214025

TRI31
E3 ubiquitin-protein ligase TRIM31

3

12

Small-scale

0.678

High

214044

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

3

5

Small-scale

0.678

High

214065

UBP18
Ubl carboxyl-terminal hydrolase 18

4

5

Small-scale

0.676

High

143504

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

3

7

Small-scale

0.667

High

155884

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.665

High

213803

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

13

Small-scale

0.665

High

213954

TAOK1
Serine/threonine-protein kinase TAO1

1

11

Small-scale

0.665

High

213984

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

19

Small-scale

0.665

High

214028

STRAB
STE20-related kinase adapter protein beta

1

15

Small-scale

0.665

High

214063

TAOK2
Serine/threonine-protein kinase TAO2

1

17

Small-scale

0.665

High

213942

MK06
Mitogen-activated protein kinase 6

1

15

High-throughput

0.656

High

213964

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

3

5

Small-scale

0.650

High

214020

CAR11
Caspase recruitment domain-containing protein 11

3

13

Small-scale

0.640

High

214042

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

3

5

Small-scale

0.640

High

213799

PRS6A
26S proteasome regulatory subunit 6A

3

0

High-throughput

0.638

High

213966

CARME
Carnosine N-methyltransferase

3

0

High-throughput

0.638

High

214076

CARD8
Caspase recruitment domain-containing protein 8

3

0

High-throughput

0.638

High

213917

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

2

7

Small-scale

0.629

High

213968

PCD20
Protocadherin-20

2

4

High-throughput

0.628

High

213969

I17RC
Interleukin-17 receptor C

2

2

High-throughput

0.628

High

214011

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

2

4

High-throughput

0.628

High

214016

AASD1
Alanyl-tRNA editing protein Aarsd1

2

1

High-throughput

0.628

High

214037

SYNCI
Syncoilin

2

1

High-throughput

0.628

High

214091

EMIL1
EMILIN-1

2

1

High-throughput

0.628

High

213977

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

12

Small-scale

0.625

High

213846

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

2

9

Small-scale

0.624

High

155145

SOCS7
Suppressor of cytokine signaling 7

1

20

Small-scale

0.618

High

161904

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

20

Small-scale

0.618

High

193472

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

7

Small-scale

0.618

High

213744

SASH1
SAM and SH3 domain-containing protein 1

1

2

Small-scale

0.618

High

213750

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

20

Small-scale

0.618

High

213757

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

213760

RASH
GTPase HRas

1

4

Small-scale

0.618

High

213806

FLNA
Filamin-A

1

4

High-throughput

0.618

High

213824

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

13

Small-scale

0.618

High

213842

TGFR2
TGF-beta receptor type-2

1

20

Small-scale

0.618

High

213854

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.618

High

213877

ANM2
Protein arginine N-methyltransferase 2

1

1

High-throughput

0.618

High

213878

SIK1
Serine/threonine-protein kinase SIK1

1

10

Small-scale

0.618

High

213903

CNTN2
Contactin-2

1

4

Small-scale

0.618

High

213952

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.618

High

214034

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.618

High

214077

SIK3
Serine/threonine-protein kinase SIK3

1

8

Small-scale

0.618

High

214079

M3K2
Mitogen-activated protein kinase kinase kinase 2

1

7

Small-scale

0.618

High

213725

SMAD6
Mothers against decapentaplegic homolog 6

2

9

Small-scale

0.612

High

213829

PEBP1
Phosphatidylethanolamine-binding protein 1

2

1

Small-scale

0.611

High

213890

RACK1
Small ribosomal subunit protein RACK1

2

1

Small-scale

0.611

High

213772

TY3H
Tyrosine 3-monooxygenase

2

0

High-throughput

0.602

High

213912

SCRN1
Secernin-1

2

0

High-throughput

0.602

High

213727

CIKS
E3 ubiquitin ligase TRAF3IP2

2

1

Small-scale

0.601

High

213752

BCL10
B-cell lymphoma/leukemia 10

2

1

Small-scale

0.601

High

214000

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

10

High-throughput

0.601

High

214054

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

2

10

Small-scale

0.601

High

213740

PPM1B
Protein phosphatase 1B

1

7

Small-scale

0.597

High

213729

PRKN
E3 ubiquitin-protein ligase parkin

2

10

High-throughput

0.584

High

213784

BIP
Endoplasmic reticulum chaperone BiP

2

7

High-throughput

0.584

High

213921

ATM
Serine-protein kinase ATM

2

6

Small-scale

0.584

High

213996

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

10

Small-scale

0.584

High

214066

CHIP
E3 ubiquitin-protein ligase CHIP

2

8

Small-scale

0.584

High

213987

FBXW5
F-box/WD repeat-containing protein 5

2

0

Small-scale

0.576

High

213993

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

1

2

Small-scale

0.573

High

214001

PKH4B
Pleckstrin homology domain-containing family G member 4B

2

3

High-throughput

0.571

High

169333

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

11

Small-scale

0.561

High

213918

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.561

High

213944

PPM1L
Protein phosphatase 1L

1

7

Small-scale

0.561

High

213976

CALL6
Calmodulin-like protein 6

1

1

Small-scale

0.561

High

214043

UBP29
Ubiquitin carboxyl-terminal hydrolase 29

1

10

Small-scale

0.561

High

213957

JAZF1
Juxtaposed with another zinc finger protein 1

2

0

Small-scale

0.551

High

213983

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.541

High

214038

AKTIP
AKT-interacting protein

1

1

High-throughput

0.541

High

213949

TP8L2
Tumor necrosis factor alpha-induced protein 8-like protein 2

1

0

Small-scale

0.537

High

213971

SP20H
Transcription factor SPT20 homolog

1

0

Small-scale

0.537

High

131089

CLIC1
Chloride intracellular channel protein 1

1

3

High-throughput

0.536

High

131594

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

10

High-throughput

0.536

High

213726

BUB3
Mitotic checkpoint protein BUB3

1

1

High-throughput

0.536

High

213735

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.536

High

213742

GLRX3
Glutaredoxin-3

1

6

High-throughput

0.536

High

213747

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

1

High-throughput

0.536

High

213749

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

213753

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

213771

TPM3
Tropomyosin alpha-3 chain

1

2

High-throughput

0.536

High

214008

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.536

High

213773

PDIA1
Protein disulfide-isomerase

1

5

High-throughput

0.536

High

213778

ANXA5
Annexin A5

1

2

High-throughput

0.536

High

213779

HMGB1
High mobility group protein B1

1

2

High-throughput

0.536

High

213780

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

1

High-throughput

0.536

High

213789

EF2
Elongation factor 2

1

1

High-throughput

0.536

High

213797

CBR1
Carbonyl reductase [NADPH] 1

1

1

High-throughput

0.536

High

213805

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

5

High-throughput

0.536

High

213807

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

1

High-throughput

0.536

High

213808

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

2

High-throughput

0.536

High

213811

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

1

High-throughput

0.536

High

213812

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

2

High-throughput

0.536

High

213818

HMGB2
High mobility group protein B2

1

2

High-throughput

0.536

High

213819

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

2

High-throughput

0.536

High

213822

CALR
Calreticulin

1

1

High-throughput

0.536

High

213823

CALX
Calnexin

1

1

High-throughput

0.536

High

213826

PRDX6
Peroxiredoxin-6

1

3

High-throughput

0.536

High

213827

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

3

High-throughput

0.536

High

213830

PDIA3
Protein disulfide-isomerase A3

1

4

High-throughput

0.536

High

213832

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

1

High-throughput

0.536

High

213835

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

213836

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.536

High

213839

BASI
Basigin

1

8

High-throughput

0.536

High

213847

MDHC
Malate dehydrogenase, cytoplasmic

1

1

High-throughput

0.536

High

213850

GARS
Glycine--tRNA ligase

1

1

High-throughput

0.536

High

213858

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

213860

EFTU
Elongation factor Tu, mitochondrial

1

3

High-throughput

0.536

High

213870

GDIR1
Rho GDP-dissociation inhibitor 1

1

1

High-throughput

0.536

High

213871

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.536

High

213875

HSP72
Heat shock-related 70 kDa protein 2

1

6

High-throughput

0.536

High

213880

MTPN
Myotrophin

1

11

High-throughput

0.536

High

213893

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.536

High

213895

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.536

High

213897

CYC
Cytochrome c

1

1

High-throughput

0.536

High

213910

HSP7E
Heat shock 70 kDa protein 14

1

7

High-throughput

0.536

High

213929

CUL4B
Cullin-4B

1

2

High-throughput

0.536

High

213945

C102B
Coiled-coil domain-containing protein 102B

1

1

High-throughput

0.536

High

213953

FBX50
F-box only protein 50

1

1

High-throughput

0.536

High

214004

TBCB
Tubulin-folding cofactor B

1

3

High-throughput

0.536

High

214029

SHRPN
Sharpin

1

2

High-throughput

0.536

High

214049

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

2

High-throughput

0.536

High

214086

RBM7
RNA-binding protein 7

1

1

High-throughput

0.536

High

214087

PCDB6
Protocadherin beta-6

1

1

High-throughput

0.536

High

213788

SKIL
Ski-like protein

1

1

Small-scale

0.529

High

136645

TRAF5
TNF receptor-associated factor 5

1

20

Small-scale

0.515

High

177632

SMAD7
Mothers against decapentaplegic homolog 7

1

9

Small-scale

0.515

High

213955

MAVS
Mitochondrial antiviral-signaling protein

1

2

Small-scale

0.515

High

213994

I17RA
Interleukin-17 receptor A

1

1

Small-scale

0.515

High

214023

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

6

Small-scale

0.515

High

214082

DAAM1
Disheveled-associated activator of morphogenesis 1

1

3

High-throughput

0.515

High

214094

TNR11
Tumor necrosis factor receptor superfamily member 11A

1

6

Small-scale

0.515

High

123294

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.513

High

162298

PDCD5
Programmed cell death protein 5

1

0

High-throughput

0.513

High

213748

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

213754

PNPH
Purine nucleoside phosphorylase

1

0

High-throughput

0.513

High

213755

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.513

High

213756

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.513

High

213758

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.513

High

213763

STAT
Statherin

1

0

High-throughput

0.513

High

213765

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.513

High

213783

ESTD
S-formylglutathione hydrolase

1

0

High-throughput

0.513

High

213786

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.513

High

213787

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.513

High

213801

PGAM1
Phosphoglycerate mutase 1

1

0

High-throughput

0.513

High

213809

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.513

High

213810

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.513

High

213814

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.513

High

213820

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.513

High

213825

TKT
Transketolase

1

0

High-throughput

0.513

High

213834

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

High-throughput

0.513

High

213843

TALDO
Transaldolase

1

0

High-throughput

0.513

High

213848

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

213859

MRP
MARCKS-related protein

1

0

High-throughput

0.513

High

213863

HINT1
Adenosine 5'-monophosphoramidase HINT1

1

0

High-throughput

0.513

High

213864

GDIB
Rab GDP dissociation inhibitor beta

1

0

High-throughput

0.513

High

213868

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

High-throughput

0.513

High

213873

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

213876

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.513

High

213883

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

213889

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.513

High

213907

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.513

High

213936

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.513

High

213941

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.513

High

213943

UROL1
Uromodulin-like 1

1

0

High-throughput

0.513

High

213970

NNRE
NAD(P)H-hydrate epimerase

1

0

High-throughput

0.513

High

213999

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

214005

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

214036

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

214045

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

214051

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.513

High

214068

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.513

High

214075

CNPY2
Protein canopy homolog 2

1

0

High-throughput

0.513

High

214088

PCDA8
Protocadherin alpha-8

1

0

High-throughput

0.513

High

214090

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.513

High

214092

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

213746

ELP1
Elongator complex protein 1

1

0

Small-scale

0.512

High

138358

ZN593
Zinc finger protein 593

1

1

High-throughput

0.508

High

213872

PPP5
Serine/threonine-protein phosphatase 5

1

9

High-throughput

0.508

High

213887

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

High-throughput

0.508

High

213939

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.508

High

213947

ZN746
Zinc finger protein 746

1

2

High-throughput

0.508

High

213974

BBS10
BBSome complex assembly protein BBS10

1

1

High-throughput

0.508

High

214048

RN19A
E3 ubiquitin-protein ligase RNF19A

1

4

High-throughput

0.508

High

213816

IKBA
NF-kappa-B inhibitor alpha

1

11

Small-scale

0.501

High

213831

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

Small-scale

0.501

High

213988

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

9

Small-scale

0.501

High

214081

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

3

Small-scale

0.501

High

186233

SIVA
Apoptosis regulatory protein Siva

1

0

Small-scale

0.493

High

214012

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

Small-scale

0.493

High

213768

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

213790

PDIA4
Protein disulfide-isomerase A4

1

5

High-throughput

0.489

High

213815

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

3

High-throughput

0.489

High

213828

ECHM
Enoyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.489

High

213862

TSP3
Thrombospondin-3

1

5

High-throughput

0.489

High

213956

PK1L2
Polycystin-1-like protein 2

1

5

High-throughput

0.489

High

214031

CAD23
Cadherin-23

1

2

High-throughput

0.489

High

213804

SL9A1
Sodium/hydrogen exchanger 1

1

0

High-throughput

0.480

High

142660

TRI38
E3 ubiquitin-protein ligase TRIM38

1

9

Small-scale

0.479

High

172289

XPO1
Exportin-1

1

3

High-throughput

0.479

High

178061

FYB1
FYN-binding protein 1

1

3

Small-scale

0.479

High

213731

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

213733

WDR1
WD repeat-containing protein 1

1

1

Small-scale

0.479

High

213738

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

8

Small-scale

0.479

High

213739

TIPRL
TIP41-like protein

1

1

Small-scale

0.479

High

213743

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

213745

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

10

Small-scale

0.479

High

213751

SNAI1
Zinc finger protein SNAI1

1

7

High-throughput

0.479

High

213766

TBB4A
Tubulin beta-4A chain

1

7

High-throughput

0.479

High

213767

HSPB1
Heat shock protein beta-1

1

1

Small-scale

0.479

High

213769

ISG15
Ubiquitin-like protein ISG15

1

7

Small-scale

0.479

High

213774

TBB5
Tubulin beta chain

1

7

High-throughput

0.479

High

213775

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.479

High

213785

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

213792

TRI27
Zinc finger protein RFP

1

8

Small-scale

0.479

High

213794

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

213796

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

213798

DDX5
Probable ATP-dependent RNA helicase DDX5

1

4

High-throughput

0.479

High

213800

EGR1
Early growth response protein 1

1

4

High-throughput

0.479

High

213813

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

213821

PYR1
Multifunctional protein CAD

1

2

High-throughput

0.479

High

213833

DNJA1
DnaJ homolog subfamily A member 1

1

3

High-throughput

0.479

High

213837

HS71L
Heat shock 70 kDa protein 1-like

1

6

High-throughput

0.479

High

213840

TRI23
E3 ubiquitin-protein ligase TRIM23

1

3

High-throughput

0.479

High

213844

HSPA9
Stress-70 protein, mitochondrial

1

12

High-throughput

0.479

High

213849

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

213851

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

213853

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

213857

YAP1
Transcriptional coactivator YAP1

1

12

High-throughput

0.479

High

213861

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

213874

HIRA
Protein HIRA

1

1

Small-scale

0.479

High

213882

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

213884

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

213891

ACTG
Actin, cytoplasmic 2

1

3

High-throughput

0.479

High

213894

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

Small-scale

0.479

High

213898

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.479

High

213905

TF65
Transcription factor p65

1

3

High-throughput

0.479

High

213915

NFX1
Transcriptional repressor NF-X1

1

6

High-throughput

0.479

High

213920

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.479

High

213925

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

213928

CUL1
Cullin-1

1

2

Small-scale

0.479

High

213931

TRI14
Tripartite motif-containing protein 14

1

12

Small-scale

0.479

High

213933

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

13

Small-scale

0.479

High

213935

DAZP2
DAZ-associated protein 2

1

1

Small-scale

0.479

High

213946

GRAM4
GRAM domain-containing protein 4

1

1

Small-scale

0.479

High

213950

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

213959

MIB1
E3 ubiquitin-protein ligase MIB1

1

10

High-throughput

0.479

High

213960

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

2

Small-scale

0.479

High

213965

FBXW8
F-box/WD repeat-containing protein 8

1

4

Small-scale

0.479

High

213972

I17RD
Interleukin-17 receptor D

1

1

Small-scale

0.479

High

213980

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

213981

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

213982

KAT2A
Histone acetyltransferase KAT2A

1

1

Small-scale

0.479

High

213985

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

3

High-throughput

0.479

High

213986

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

213989

MIB2
E3 ubiquitin-protein ligase MIB2

1

11

Small-scale

0.479

High

213990

OPTN
Optineurin

1

6

High-throughput

0.479

High

213991

RNF31
E3 ubiquitin-protein ligase RNF31

1

7

High-throughput

0.479

High

213992

SGF29
SAGA-associated factor 29

1

1

Small-scale

0.479

High

213995

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

1

5

Small-scale

0.479

High

213997

TNIP3
TNFAIP3-interacting protein 3

1

4

Small-scale

0.479

High

213998

SNX27
Sorting nexin-27

1

5

High-throughput

0.479

High

214010

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

214013

LZTS2
Leucine zipper putative tumor suppressor 2

1

3

High-throughput

0.479

High

214014

TRI56
E3 ubiquitin-protein ligase TRIM56

1

11

Small-scale

0.479

High

214017

TRAF4
TNF receptor-associated factor 4

1

20

Small-scale

0.479

High

214018

TBB2B
Tubulin beta-2B chain

1

7

High-throughput

0.479

High

214019

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

2

Small-scale

0.479

High

214026

TRIM5
Tripartite motif-containing protein 5

1

9

Small-scale

0.479

High

214027

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

214030

ZBP1
Z-DNA-binding protein 1

1

1

Small-scale

0.479

High

214033

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

2

Small-scale

0.479

High

214035

RN167
E3 ubiquitin-protein ligase RNF167

1

2

Small-scale

0.479

High

214039

TRI45
E3 ubiquitin-protein ligase TRIM45

1

12

Small-scale

0.479

High

214040

ZDH11
Palmitoyltransferase ZDHHC11

1

2

Small-scale

0.479

High

214053

HDAC6
Protein deacetylase HDAC6

1

3

Small-scale

0.479

High

214055

FXL17
F-box/LRR-repeat protein 17

1

20

Small-scale

0.479

High

214056

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

214057

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

214058

FBW1B
F-box/WD repeat-containing protein 11

1

3

Small-scale

0.479

High

214060

FBX4
F-box only protein 4

1

1

Small-scale

0.479

High

214062

FBXW2
F-box/WD repeat-containing protein 2

1

4

Small-scale

0.479

High

214067

CSN3
COP9 signalosome complex subunit 3

1

3

High-throughput

0.479

High

214069

Q9UQC1
Heat shock protein 72

1

8

High-throughput

0.479

High

214072

RUVB2
RuvB-like 2

1

5

High-throughput

0.479

High

214073

RUVB1
RuvB-like 1

1

5

High-throughput

0.479

High

214074

FBW1A
F-box/WD repeat-containing protein 1A

1

2

Small-scale

0.479

High

214083

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

7

Small-scale

0.479

High

214089

MAGD1
Melanoma-associated antigen D1

1

4

Small-scale

0.479

High

125088

LEG9
Galectin-9

1

0

High-throughput

0.458

High

213728

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

213730

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

213736

ERLN1
Erlin-1

1

0

Small-scale

0.458

High

213737

TADA3
Transcriptional adapter 3

1

0

Small-scale

0.458

High

213741

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

213762

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

213770

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

213881

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

Small-scale

0.458

High

213886

H4
Histone H4

1

0

High-throughput

0.458

High

213888

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

213900

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.458

High

213901

NC2B
Protein Dr1

1

0

Small-scale

0.458

High

213911

BST2
Bone marrow stromal antigen 2

1

0

Small-scale

0.458

High

213922

IFIT5
Interferon-induced protein with tetratricopeptide repeats 5

1

0

Small-scale

0.458

High

213932

KEAP1
Kelch-like ECH-associated protein 1

1

0

Small-scale

0.458

High

213934

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

213951

FBW12
F-box/WD repeat-containing protein 12

1

0

Small-scale

0.458

High

213975

FBX30
F-box only protein 30

1

0

Small-scale

0.458

High

213979

EDAD
Ectodysplasin-A receptor-associated adapter protein

1

0

Small-scale

0.458

High

214003

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

214015

NFIP1
NEDD4 family-interacting protein 1

1

0

Small-scale

0.458

High

214041

CSN7B
COP9 signalosome complex subunit 7b

1

0

High-throughput

0.458

High

214047

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

214061

FBXL3
F-box/LRR-repeat protein 3

1

0

Small-scale

0.458

High

214064

YETS2
YEATS domain-containing protein 2

1

0

Small-scale

0.458

High

214078

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.458

High

214080

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

Small-scale

0.458

High

213759

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.445

High

213782

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

213852

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

1

High-throughput

0.445

High

213892

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

5

Small-scale

0.445

High

213923

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

213909

LG3BP
Galectin-3-binding protein

1

1

Small-scale

0.437

High

213930

TRI29
Tripartite motif-containing protein 29

1

13

Small-scale

0.437

High

213948

FBX42
F-box only protein 42

1

6

Small-scale

0.437

High

214002

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

213764

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.279

Low

213791

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

213963

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

0

High-throughput

0.279

Low

213978

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

213734

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.265

Low

213937

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

213961

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

213962

F177A
Protein FAM177A1

1

0

Small-scale

0.249

Low

213973

RLA0L
Putative ribosomal protein uL10-like

1

0

High-throughput

0.249

Low

214022

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.249

Low

214084

PKHM1
Pleckstrin homology domain-containing family M member 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025