HitPredict

Interactor 1: TXNIP (Q5M7W1)
Thioredoxin-interacting protein (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 394 Rn			1 810
+	Rn
		708822 ARRB2_RAT (15-360): 1.72e-79: 251: 13.71		UBC_RAT (1-810): 0: 1000: 100.00
+	Rn
		708816 ARRB1_RAT (25-350): 3.49e-76: 243: 12.67		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		507587 ARRB2_HUMAN (15-360): 5.84e-82: 258: 13.49		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		507675 ARRB1_HUMAN (25-358): 3.38e-78: 248: 12.66		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		732525 ARRB2_HUMAN (15-360): 5.84e-82: 258: 13.49		RS27A_HUMAN (685-760): 5.1e-42: 152: 100.00
+	Hs
		732619 ARRB2_HUMAN (15-360): 5.84e-82: 258: 13.49		Q5RKT7_HUMAN (685-760): 2.69e-42: 152: 100.00
+	Hs
		732623 ARRB2_HUMAN (15-360): 5.84e-82: 258: 13.49		Q5UGI3_HUMAN (685-801): 3.73e-40: 146: 83.76
+	Hs
		882441 ARRB1_HUMAN (25-358): 3.38e-78: 248: 12.66		RS27A_HUMAN (685-760): 5.1e-42: 152: 100.00
+	Hs
		882509 ARRB1_HUMAN (25-358): 3.38e-78: 248: 12.66		Q5RKT7_HUMAN (685-760): 2.69e-42: 152: 100.00
+	Hs
		882513 ARRB1_HUMAN (25-358): 3.38e-78: 248: 12.66		Q5UGI3_HUMAN (685-801): 3.73e-40: 146: 83.76
+	Hs
		507095 ARRB2_HUMAN (15-360): 5.84e-82: 258: 13.49		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		732622 ARRB2_HUMAN (15-360): 5.84e-82: 258: 13.49		Q5U5U6_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		507115 ARRB1_HUMAN (25-358): 3.38e-78: 248: 12.66		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Hs
		882511 ARRB1_HUMAN (25-358): 3.38e-78: 248: 12.66		Q5U5U6_HUMAN (1-77): 1.17e-26: 110: 98.70