HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Gal-bind_lectin~V-set
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 646
+	Hs
		121151 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		CD166_HUMAN (13-607): 2.71e-98: 314: 22.33
+	Hs
		119364 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		CD166_HUMAN (13-607): 2.71e-98: 314: 22.33
+	Hs
		1045045 LEG9B_HUMAN (3-316): 3.69e-110: 325: 30.47		CD166_HUMAN (13-607): 2.71e-98: 314: 22.33
+	Hs
		572314 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00
+	Hs
		449219 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00
+	Hs
		572356 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		CD166_HUMAN (13-607): 2.71e-98: 314: 22.33
+	Hs
		449258 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		CD166_HUMAN (13-607): 2.71e-98: 314: 22.33
+	Hs
		449252 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		PTK7_HUMAN (17-627): 1.64e-70: 249: 12.68