HitPredict

Interactor 1: SET (Q01105)
Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)
Gene: SET

Interactor 2: TSYL1 (Q9H0U9)
Testis-specific Y-encoded-like protein 1 (TSPY-like protein 1)
Gene: TSPYL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NAP~NAP
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly and 1 others more... GO:0042393 - histone binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 290 Hs			1 437
+	Hs
		1151427 Q6FI91_HUMAN (44-234): 2.69e-85: 263: 38.74		Q6FI91_HUMAN (1-437): 0: 542: 99.09
+	Hs
		1328205 TSYL1_HUMAN (44-234): 2.32e-85: 264: 38.74		TSYL1_HUMAN (1-437): 0: 540: 100.00
+	Hs
		1328217 TSYL1_HUMAN (44-234): 2.32e-85: 264: 38.74		TSYL4_HUMAN (1-437): 2.62e-163: 467: 52.02
+	Hs
		963901 SET_HUMAN (1-236): 6.45e-89: 268: 100.00		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		1328206 TSYL1_HUMAN (44-234): 2.32e-85: 264: 38.74		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		1151432 Q6FI91_HUMAN (44-234): 2.69e-85: 263: 38.74		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		1237381 TSYL6_HUMAN (10-234): 1.79e-80: 250: 32.76		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		965385 TSYL5_HUMAN (2-257): 3.11e-86: 265: 32.69		TSPY1_HUMAN (135-429): 6.88e-94: 287: 37.29
+	Hs
		63699 TSYL4_HUMAN (31-235): 7.34e-85: 261: 36.59		TSPY2_HUMAN (135-429): 3.07e-95: 290: 36.95
+	Hs
		963791 SET_HUMAN (1-236): 6.45e-89: 268: 100.00		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Hs
		483599 SET_HUMAN (1-236): 6.45e-89: 268: 100.00		SETLP_HUMAN (185-412): 8.67e-85: 263: 31.22
+	Hs
		1306101 TSYL4_HUMAN (31-235): 7.34e-85: 261: 36.59		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		876880 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		876731 NP1L1_HUMAN (2-278): 1.56e-83: 258: 18.13		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Hs
		1306080 NP1L4_HUMAN (4-242): 5.86e-81: 250: 18.81		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Zm
		1226601 Q8L8G5_MAIZE (3-286): 8.23e-81: 250: 23.70		Q94F79_MAIZE (200-408): 2.11e-68: 219: 30.46