HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: NECT1 (Q15223)
Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111)
Gene: NECTIN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Gal-bind_lectin~V-set
Common GO terms	GO:0016020 - membrane GO:0030246 - carbohydrate binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 517
+	Hs
		121215 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		NECT3_HUMAN (24-517): 1.69e-62: 215: 29.03
+	Hs
		119138 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		PVR_HUMAN (25-422): 3.69e-77: 250: 28.22
+	Hs
		545068 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		PVR_HUMAN (25-422): 3.69e-77: 250: 28.22
+	Hs
		572445 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		CADM1_HUMAN (19-394): 1.45e-68: 228: 19.02
+	Hs
		449360 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		NECT3_HUMAN (24-517): 1.69e-62: 215: 29.03
+	Hs
		449334 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		NEO1_HUMAN (28-498): 1.77e-43: 167: 14.49