Protein: TRMB
tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA methylguanosine methyltransferase 1) (tRNA(m7G46)-methyltransferase)

Gene: TRMB, Mettl1
Organism: Drosophila melanogaster
Interactions: 163
UniProt ID: O77263

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0005634 - nucleus
GO:0006400 - tRNA modification
GO:0008176 - tRNA (guanine(46)-N7)-methyltransferase activity
GO:0030488 - tRNA methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

305297

WUHO
tRNA

2

2

Small-scale

0.789

High

305256

PYRD1
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1

1

1

High-throughput

0.508

High

305247

Q9VF77
FI16517p1

1

0

High-throughput

0.486

High

235000

O46087
EG:63B12.7 protein

1

0

Small-scale

0.481

High

305218

CORT
Protein cortex

1

0

Small-scale

0.481

High

305174

PSB1
Proteasome subunit beta type-1

1

2

High-throughput

0.445

High

305176

TTKA
Protein tramtrack, alpha isoform

1

1

Small-scale

0.445

High

305189

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

Small-scale

0.445

High

305190

NLP
Nucleoplasmin-like protein

1

1

High-throughput

0.445

High

305203

LOLA4
Longitudinals lacking protein, isoforms F/I/K/T

1

1

Small-scale

0.445

High

305230

THIO2
Thioredoxin-2

1

1

High-throughput

0.445

High

305233

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.445

High

305236

Q9VAC4
GEO09167p1

1

1

High-throughput

0.445

High

305266

PSB4
Proteasome subunit beta type-4

1

2

High-throughput

0.445

High

305280

Q9VUC1
Hsc70Cb, isoform A

1

1

High-throughput

0.445

High

305300

PSB3
Proteasome subunit beta type-3

1

2

High-throughput

0.445

High

305303

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.445

High

305272

TM10A
tRNA

1

0

High-throughput

0.438

High

194980

O16043
Anon1A4

1

0

High-throughput

0.426

High

235081

O46173
Y-box protein

1

0

Small-scale

0.426

High

305160

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.426

High

305161

O97102
Small ubiquitin-related modifier

1

0

High-throughput

0.426

High

305166

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.426

High

305167

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.426

High

305168

DEC13
Defective chorion protein, FC177 isoform

1

0

Small-scale

0.426

High

305169

NCD
Protein claret segregational

1

0

Small-scale

0.426

High

305170

ANX10
Annexin B10

1

0

High-throughput

0.426

High

305177

MOEH
Moesin/ezrin/radixin homolog 1

1

0

High-throughput

0.426

High

305180

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

305192

Q76NR6
Regucalcin

1

0

High-throughput

0.426

High

305195

Q7JXC4
CG6459 protein

1

0

High-throughput

0.426

High

305198

Q7K148
Proteasome subunit beta

1

0

High-throughput

0.426

High

305200

TERA
Transitional endoplasmic reticulum ATPase TER94

1

0

High-throughput

0.426

High

305201

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

0

High-throughput

0.426

High

305204

Q86BR8
Mitochondrial transcription factor A, isoform B

1

0

Small-scale

0.426

High

305205

ATBP
AT-rich binding protein

1

0

Small-scale

0.426

High

305206

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.426

High

305210

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.426

High

305211

Q8MYY7
RE44624p

1

0

High-throughput

0.426

High

305212

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

0

High-throughput

0.426

High

305214

Q8T0L3
E1 ubiquitin-activating enzyme

1

0

High-throughput

0.426

High

305220

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.426

High

305221

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.426

High

305225

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.426

High

305226

RUVB2
RuvB-like helicase 2

1

0

Small-scale

0.426

High

305229

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.426

High

305234

Q9V9U3
LD45254p

1

0

High-throughput

0.426

High

305248

MBDR2
Protein MBD-R2

1

0

Small-scale

0.426

High

305250

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.426

High

305251

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.426

High

305252

Q9VHI1
Hyrax

1

0

Small-scale

0.426

High

305271

BACC
Bacchus

1

0

High-throughput

0.426

High

305274

Q9VRL1
GEO06356p1

1

0

High-throughput

0.426

High

305276

Q9VRX7
LD29573p

1

0

Small-scale

0.426

High

305284

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.426

High

305289

Q9W0H8
Reticulocalbin-3

1

0

High-throughput

0.426

High

305290

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.426

High

305293

Q9W3J4
LD35215p

1

0

Small-scale

0.426

High

305295

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.426

High

305298

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.426

High

53950

A1Z892
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

57498

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.407

High

120604

M9PDQ9
Uncharacterized protein, isoform D

1

1

Small-scale

0.407

High

121158

ALDR
Aldo-keto reductase 1B

1

4

High-throughput

0.407

High

232059

O44384
RNA-directed DNA polymerase

1

1

Small-scale

0.407

High

305178

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

3

High-throughput

0.407

High

305181

PDI
Protein disulfide-isomerase

1

2

High-throughput

0.407

High

305183

TRXR1
Thioredoxin reductase 1, mitochondrial

1

1

High-throughput

0.407

High

305191

Q3YMU0
Protein disulfide-isomerase

1

1

High-throughput

0.407

High

305193

Q7JVH6
LD24696p

1

4

High-throughput

0.407

High

305194

Q7JX87
1-Cys peroxiredoxin

1

1

High-throughput

0.407

High

305219

IF5A
Eukaryotic translation initiation factor 5A

1

2

High-throughput

0.407

High

305228

Q9V3V2
peptidylprolyl isomerase

1

3

High-throughput

0.407

High

305231

PDIA6
Protein disulfide-isomerase A6 homolog

1

1

High-throughput

0.407

High

305249

Q9VGK3
peptidylprolyl isomerase

1

3

High-throughput

0.407

High

305254

Q9VHX4
LD24679p

1

4

High-throughput

0.407

High

305257

Q9VKB0
threonine--tRNA ligase

1

1

High-throughput

0.407

High

305261

Q9VL70
HL08109p

1

1

High-throughput

0.407

High

305262

FKB59
FK506-binding protein 59

1

2

High-throughput

0.407

High

305268

Q9VPK3
AT24407p

1

1

Small-scale

0.407

High

305277

Q9VSL2
Glutathione S transferase O3

1

1

High-throughput

0.407

High

305278

Q9VTY2
Uncharacterized protein, isoform A

1

4

High-throughput

0.407

High

305282

Q9VVL7
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.407

High

305286

CLIC
Chloride intracellular channel Clic

1

1

High-throughput

0.407

High

305288

Q9W022
GEO01508p1

1

2

High-throughput

0.407

High

305291

Q9W1H8
acetyl-CoA C-acyltransferase

1

1

Small-scale

0.407

High

305301

Q9XYZ9
Glutathione S transferase E12, isoform A

1

1

High-throughput

0.407

High

305305

Q9Y112
BcDNA.GH10614

1

4

High-throughput

0.407

High

2206

A0A0B4K5Z8
Protein transport protein SEC23

1

0

Small-scale

0.232

Low

56332

ZASP
PDZ and LIM domain protein Zasp

1

0

Small-scale

0.232

Low

57728

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.232

Low

86441

B9EQV3
Endoplasmic reticulum transmembrane protein

1

0

High-throughput

0.232

Low

86631

B9EQX1
FI10950p

1

0

Small-scale

0.232

Low

121652

M9PFV8
Regeneration, isoform B

1

0

Small-scale

0.232

Low

197711

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.232

Low

304583

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.232

Low

305162

O97428
Ciboulot, isoform A

1

0

High-throughput

0.232

Low

305163

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.232

Low

305164

MYSA
Myosin heavy chain, muscle

1

0

Small-scale

0.232

Low

305165

NDKA
Nucleoside diphosphate kinase

1

0

High-throughput

0.232

Low

305171

CALR
Calreticulin

1

0

High-throughput

0.232

Low

305172

UCHL
Ubiquitin carboxyl-terminal hydrolase

1

0

High-throughput

0.232

Low

305173

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.232

Low

305175

RL27A
Large ribosomal subunit protein uL15

1

0

Small-scale

0.232

Low

305179

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.232

Low

305182

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

305184

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.232

Low

305185

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

305186

Q0E8K5
AT10158p

1

0

Small-scale

0.232

Low

305187

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.232

Low

305188

RL29
Large ribosomal subunit protein eL29

1

0

Small-scale

0.232

Low

305196

Q7JZ53
U3 small nucleolar ribonucleoprotein protein IMP3

1

0

Small-scale

0.232

Low

305197

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

Small-scale

0.232

Low

305199

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

305202

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.232

Low

305207

Q8IQZ7
FI19014p1

1

0

High-throughput

0.232

Low

305208

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.232

Low

305209

Q8MNR4
Uncharacterized protein

1

0

Small-scale

0.232

Low

305213

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.232

Low

305215

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

305216

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.232

Low

305217

FAXC
Failed axon connections

1

0

High-throughput

0.232

Low

305222

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.232

Low

305223

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

0

High-throughput

0.232

Low

305224

GCSH
Glycine cleavage system H protein, mitochondrial

1

0

High-throughput

0.232

Low

305227

Q9V3P2
Nucleolar protein 10

1

0

Small-scale

0.232

Low

305232

Q9V4B8
RE68558p

1

0

Small-scale

0.232

Low

305235

Q9VAC1
GM14349p

1

0

High-throughput

0.232

Low

305237

Q9VAN7
Phosphoglycerate mutase

1

0

High-throughput

0.232

Low

305238

Q9VAY2
Heat shock protein 83

1

0

High-throughput

0.232

Low

305239

Q9VBR6
RE74917p

1

0

High-throughput

0.232

Low

305240

Q9VCK6
LD34157p

1

0

High-throughput

0.232

Low

305241

Q9VD02
GH14779p

1

0

High-throughput

0.232

Low

305242

Q9VD29
small monomeric GTPase

1

0

High-throughput

0.232

Low

305243

Q9VE75
V-type proton ATPase subunit a

1

0

Small-scale

0.232

Low

305244

Q9VEB1
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

305245

Q9VEC4
Uncharacterized protein, isoform A

1

0

Small-scale

0.232

Low

305246

FLNA
Filamin-A

1

0

High-throughput

0.232

Low

305253

Q9VHN7
transketolase

1

0

High-throughput

0.232

Low

305255

Q9VIE8
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.232

Low

305258

Q9VKW5
Prolyl endopeptidase

1

0

High-throughput

0.232

Low

305259

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.232

Low

305260

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

0

High-throughput

0.232

Low

305263

AK200
A-kinase anchor protein 200

1

0

High-throughput

0.232

Low

305264

TIG
Tiggrin

1

0

Small-scale

0.232

Low

305265

Q9VMU6
LD31822p

1

0

High-throughput

0.232

Low

305267

Q9VNB2
RE42193p

1

0

High-throughput

0.232

Low

305269

Q9VPN5
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.232

Low

305270

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.232

Low

305273

Q9VRD6
NTF2-related export protein

1

0

High-throughput

0.232

Low

305275

Q9VRP2
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

305279

Q9VU35
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.232

Low

305281

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.232

Low

305283

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.232

Low

305285

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.232

Low

305287

Q9VZI1
Transgelin

1

0

High-throughput

0.232

Low

305292

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.232

Low

305294

Q9W3X6
fumarate hydratase

1

0

High-throughput

0.232

Low

305296

CISY
Probable citrate synthase, mitochondrial

1

0

High-throughput

0.232

Low

305299

Q9W478
RE43153p

1

0

High-throughput

0.232

Low

305302

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.232

Low

305304

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.232

Low

305306

X2JAM4
Supervillin, isoform AE

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025