Interactor 1: SYP (Q8I5R7)
Proline--tRNA ligase (PfPRS) (EC 6.1.1.15) (Prolyl-tRNA synthetase) (PfProRS)
Gene: proRS

Interactor 2: SYP (Q8I5R7)
Proline--tRNA ligase (PfPRS) (EC 6.1.1.15) (Prolyl-tRNA synthetase) (PfProRS)
Gene: proRS

Species: Plasmodium falciparum 3D7

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 25817387
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HGTP_anticodon~HGTP_anticodon, HGTP_anticodon~ProRS-C_1, HGTP_anticodon~tRNA-synt_2b, ProRS-C_1~ProRS-C_1, ProRS-C_1~tRNA-synt_2b, tRNA-synt_2b~tRNA-synt_2b, tRNA_edit~tRNA_edit
Common GO terms GO:0004827 - proline-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006418 - tRNA aminoacylation for protein translation
GO:0006433 - prolyl-tRNA aminoacylation
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 746
Pf

1 746
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Ec
+ Sc
+ Ca
+ Zm
+ Ec
+ Hp

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Last updated: 15 Jul 2024