HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: S12A6 (Q9UHW9)
Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)
Gene: SLC12A6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 1150
+	Hs
		119555 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Hs
		1107986 LEG9B_HUMAN (3-316): 3.69e-110: 325: 30.47		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Hs
		1150403 LEG9C_HUMAN (3-316): 4.69e-110: 325: 30.47		S12A6_HUMAN (1-1150): 0: 1261: 100.00
+	Hs
		121232 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		121236 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		119565 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		1107988 LEG9B_HUMAN (3-316): 3.69e-110: 325: 30.47		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		119583 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		1107989 LEG9B_HUMAN (3-316): 3.69e-110: 325: 30.47		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		121133 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		119282 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		873928 LEG9B_HUMAN (3-316): 3.69e-110: 325: 30.47		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		873935 LEG9C_HUMAN (3-316): 4.69e-110: 325: 30.47		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		121209 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		S12A9_HUMAN (184-977): 1.39e-156: 492: 25.06
+	Hs
		119512 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		S12A9_HUMAN (184-977): 1.39e-156: 492: 25.06
+	Hs
		119269 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		854888 LEG9B_HUMAN (3-316): 3.69e-110: 325: 30.47		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		119196 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		CTR1_HUMAN (231-668): 3.36e-86: 294: 13.90
+	Hs
		676558 LEG9C_HUMAN (3-316): 4.69e-110: 325: 30.47		CTR1_HUMAN (231-668): 3.36e-86: 294: 13.90
+	Hs
		119332 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		LAT1_HUMAN (231-752): 6.68e-80: 273: 12.08