HitPredict

Interactor 1: MIRO (Q8IMX7)
Mitochondrial Rho GTPase (Miro) (dMiro) (EC 3.6.5.-)
Gene: MIRO

Interactor 2: MILT (Q960V3)
Trafficking kinesin-binding protein milt (Protein milton)
Gene: MILT

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	16717129, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019896 - axonal transport of mitochondrion GO:0031410 - cytoplasmic vesicle GO:1904115 - axon cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 652 Dm			1 1122
+	Hs
		230512 MIRO1_HUMAN (9-644): 0: 739: 50.78		TRAK2_HUMAN (139-911): 4.63e-34: 143: 24.41
+	Hs
		230511 MIRO2_HUMAN (9-625): 0: 732: 48.23		TRAK2_HUMAN (139-911): 4.63e-34: 143: 24.41
+	Hs
		1220736 MIRO1_HUMAN (9-644): 0: 739: 50.78		TRAK1_HUMAN (34-258): 2.74e-09: 63.8: 10.55
+	Hs
		1220707 MIRO2_HUMAN (9-625): 0: 732: 48.23		TRAK1_HUMAN (34-258): 2.74e-09: 63.8: 10.55
+	Hs
		764619 RAB1A_HUMAN (1-215): 7.46e-75: 240: 19.36		CUX1_HUMAN (113-843): 1.36e-40: 165: 14.21
+	Hs
		256706 RB11B_HUMAN (1-229): 3.64e-74: 239: 20.35		RFIP3_HUMAN (126-449): 9.88e-41: 164: 19.94
+	Hs
		256700 RB11A_HUMAN (1-227): 5.72e-74: 238: 20.09		RFIP3_HUMAN (126-449): 9.88e-41: 164: 19.94
+	Mm
		48772 RB11B_MOUSE (1-229): 7.32e-74: 238: 20.35		BICL1_MOUSE (154-418): 1.26e-35: 145: 20.37
+	Hs
		900754 RHOA_HUMAN (13-212): 2.54e-72: 233: 23.83		MY18A_HUMAN (17-780): 4.39e-29: 128: 8.97
+	Hs
		901094 RHOA_HUMAN (13-212): 2.54e-72: 233: 23.83		MRCKB_HUMAN (10-478): 1.05e-26: 120: 9.98
+	Hs
		254466 RB11A_HUMAN (1-227): 5.72e-74: 238: 20.09		ROCK2_HUMAN (194-677): 6.79e-23: 108: 8.22
+	Hs
		914103 RB11A_HUMAN (1-227): 5.72e-74: 238: 20.09		GRDN_HUMAN (13-614): 4.72e-23: 108: 9.33
+	Hs
		254464 RHOA_HUMAN (13-212): 2.54e-72: 233: 23.83		ROCK2_HUMAN (194-677): 6.79e-23: 108: 8.22
+	Hs
		900534 RHOA_HUMAN (13-212): 2.54e-72: 233: 23.83		GRDN_HUMAN (13-614): 4.72e-23: 108: 9.33
+	Hs
		148636 RAB1A_HUMAN (1-215): 7.46e-75: 240: 19.36		CTRO_HUMAN (4-563): 5.37e-19: 95.7: 9.04
+	Hs
		148608 RHOA_HUMAN (13-212): 2.54e-72: 233: 23.83		CTRO_HUMAN (4-563): 5.37e-19: 95.7: 9.04
+	Mm
		823539 RHOA_MOUSE (13-212): 2.54e-72: 233: 23.83		CTRO_MOUSE (244-793): 9.76e-17: 88.1: 9.98
+	Hs
		914124 RB11A_HUMAN (1-227): 5.72e-74: 238: 20.09		MRCKA_HUMAN (1-347): 6.14e-14: 79.2: 10.59
+	Rn
		92842 RHOA_RAT (13-212): 2.54e-72: 233: 23.83		CTRO_RAT (257-793): 5.68e-14: 79.3: 6.75
+	Hs
		900570 RHOA_HUMAN (13-212): 2.54e-72: 233: 23.83		MRCKA_HUMAN (1-347): 6.14e-14: 79.2: 10.59