Protein: CDK18
Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)

Gene: CDK18
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q07002

Gene Ontology (top 5):
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016310 - phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

431772

HS90A
Heat shock protein HSP 90-alpha

4

20

High-throughput

0.886

High

277497

CCNK
Cyclin-K

3

20

High-throughput

0.861

High

960358

CDK16
Cyclin-dependent kinase 16

3

16

High-throughput

0.847

High

989671

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

3

10

High-throughput

0.847

High

989678

DUS7
Dual specificity protein phosphatase 7

3

6

High-throughput

0.847

High

989711

CDK15
Cyclin-dependent kinase 15

3

15

High-throughput

0.847

High

438101

HS90B
Heat shock protein HSP 90-beta

3

20

High-throughput

0.827

High

509645

UBL4A
Ubiquitin-like protein 4A

2

11

High-throughput

0.811

High

803503

BAG6
Large proline-rich protein BAG6

2

10

High-throughput

0.811

High

50906

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

13

High-throughput

0.783

High

673144

CCND3
G1/S-specific cyclin-D3

2

20

High-throughput

0.783

High

989669

LIPA1
Liprin-alpha-1

2

13

High-throughput

0.783

High

989691

ZN774
Zinc finger protein 774

2

1

High-throughput

0.783

High

989717

ZN426
Zinc finger protein 426

2

3

High-throughput

0.783

High

454826

FGR
Tyrosine-protein kinase Fgr

2

14

High-throughput

0.754

High

683288

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.704

High

926960

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.699

High

646826

1433T
14-3-3 protein theta

4

20

Small-scale

0.696

High

134376

ACKR2
Atypical chemokine receptor 2

2

2

High-throughput

0.694

High

380769

S100B
Protein S100-B

1

12

High-throughput

0.691

High

414886

CDK1
Cyclin-dependent kinase 1

1

16

High-throughput

0.691

High

758199

CDN1A
Cyclin-dependent kinase inhibitor 1

1

20

High-throughput

0.691

High

960275

CDK5
Cyclin-dependent kinase 5

1

16

High-throughput

0.691

High

960435

CDK17
Cyclin-dependent kinase 17

1

16

High-throughput

0.691

High

989707

GWL
Serine/threonine-protein kinase greatwall

1

13

High-throughput

0.691

High

989720

RBM4
RNA-binding protein 4

1

8

High-throughput

0.691

High

989732

RALY
RNA-binding protein Raly

1

3

High-throughput

0.691

High

989684

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

15

High-throughput

0.675

High

904478

1433G
14-3-3 protein gamma

3

20

High-throughput

0.675

High

909472

1433E
14-3-3 protein epsilon

3

9

High-throughput

0.671

High

989687

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

2

High-throughput

0.665

High

989733

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.665

High

981945

1433F
14-3-3 protein eta

3

20

High-throughput

0.662

High

295995

MTA2
Metastasis-associated protein MTA2

3

3

High-throughput

0.656

High

989698

TTC29
Tetratricopeptide repeat protein 29

3

0

High-throughput

0.628

High

568639

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

9

High-throughput

0.618

High

989672

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

17

High-throughput

0.618

High

989677

CDC37
Hsp90 co-chaperone Cdc37

1

7

High-throughput

0.618

High

989681

LARP7
La-related protein 7

1

20

High-throughput

0.618

High

989692

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.618

High

989664

GOGA2
Golgin subfamily A member 2

3

17

High-throughput

0.616

High

989674

K1H1
Keratin, type I cuticular Ha1

3

6

High-throughput

0.616

High

61854

CC88B
Coiled-coil domain-containing protein 88B

2

16

High-throughput

0.606

High

118554

EYA2
Eyes absent homolog 2

2

2

High-throughput

0.606

High

445036

K1C16
Keratin, type I cytoskeletal 16

2

5

High-throughput

0.606

High

580017

K1C15
Keratin, type I cytoskeletal 15

2

5

High-throughput

0.606

High

981555

REL
Proto-oncogene c-Rel

2

4

High-throughput

0.606

High

989665

INCA1
Protein INCA1

2

1

High-throughput

0.606

High

989667

TRAF2
TNF receptor-associated factor 2

2

6

High-throughput

0.606

High

989668

TRAF1
TNF receptor-associated factor 1

2

1

High-throughput

0.606

High

989690

HMBX1
Homeobox-containing protein 1

2

11

High-throughput

0.606

High

989693

ZN438
Zinc finger protein 438

2

2

High-throughput

0.606

High

989694

TRI50
E3 ubiquitin-protein ligase TRIM50

2

6

High-throughput

0.606

High

989706

HOOK2
Protein Hook homolog 2

2

18

High-throughput

0.606

High

989709

KAD8
Adenylate kinase 8

2

2

High-throughput

0.606

High

989727

HOME3
Homer protein homolog 3

2

3

High-throughput

0.606

High

989728

ZRAN1
Ubiquitin thioesterase ZRANB1

2

3

High-throughput

0.606

High

989730

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

16

High-throughput

0.606

High

989738

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

2

18

High-throughput

0.606

High

843625

FXR1
RNA-binding protein FXR1

2

0

High-throughput

0.594

High

989710

SFXN2
Sideroflexin-2

3

2

High-throughput

0.593

High

989696

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.580

High

989724

GO45
Golgin-45

2

0

High-throughput

0.580

High

989731

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

0

High-throughput

0.580

High

989683

HS905
Putative heat shock protein HSP 90-alpha A5

1

20

High-throughput

0.575

High

536798

TRI27
Zinc finger protein RFP

1

6

High-throughput

0.573

High

989688

C102B
Coiled-coil domain-containing protein 102B

1

14

High-throughput

0.573

High

989700

PNMA1
Paraneoplastic antigen Ma1

1

2

High-throughput

0.573

High

989718

KIFC3
Kinesin-like protein KIFC3

1

3

High-throughput

0.573

High

989721

TRI54
Tripartite motif-containing protein 54

1

16

High-throughput

0.573

High

989722

TSG10
Testis-specific gene 10 protein

1

18

High-throughput

0.573

High

62293

GG6L9
Golgin subfamily A member 6-like protein 9

2

13

High-throughput

0.553

High

213939

KRT86
Keratin, type II cuticular Hb6

2

1

High-throughput

0.553

High

280567

KRT34
Keratin, type I cuticular Ha4

2

6

High-throughput

0.553

High

318796

K2C75
Keratin, type II cytoskeletal 75

2

1

High-throughput

0.553

High

869365

HAP1
Huntingtin-associated protein 1

2

13

High-throughput

0.553

High

989673

RABE1
Rab GTPase-binding effector protein 1

2

13

High-throughput

0.553

High

989697

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

1

High-throughput

0.553

High

989699

CBY2
Protein chibby homolog 2

2

1

High-throughput

0.553

High

989725

GORS2
Golgi reassembly-stacking protein 2

2

4

High-throughput

0.553

High

310148

CCDB1
Cyclin-D1-binding protein 1

1

0

High-throughput

0.549

High

989702

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.549

High

358502

CO1A1
Collagen alpha-1(I) chain

1

1

High-throughput

0.536

High

531130

EF2
Elongation factor 2

1

7

High-throughput

0.536

High

573231

TCPA
T-complex protein 1 subunit alpha

1

16

High-throughput

0.536

High

770800

TCPZ
T-complex protein 1 subunit zeta

1

15

High-throughput

0.536

High

821179

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.536

High

826627

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.536

High

842836

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.536

High

843169

TCPD
T-complex protein 1 subunit delta

1

16

High-throughput

0.536

High

858614

PPP5
Serine/threonine-protein phosphatase 5

1

14

High-throughput

0.536

High

900137

RL37A
Large ribosomal subunit protein eL43

1

2

High-throughput

0.536

High

915170

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

10

High-throughput

0.536

High

943201

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.536

High

989679

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

6

High-throughput

0.536

High

989708

FUBP3
Far upstream element-binding protein 3

1

10

High-throughput

0.536

High

989714

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.536

High

989723

NSRP1
Nuclear speckle splicing regulatory protein 1

1

3

High-throughput

0.536

High

989726

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

5

High-throughput

0.536

High

989729

TRPS1
Zinc finger transcription factor Trps1

1

6

High-throughput

0.536

High

989734

CHIP
E3 ubiquitin-protein ligase CHIP

1

7

High-throughput

0.536

High

989735

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.536

High

989737

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.536

High

989689

K1C40
Keratin, type I cytoskeletal 40

1

6

High-throughput

0.523

High

989715

LZTS2
Leucine zipper putative tumor suppressor 2

1

17

High-throughput

0.523

High

989676

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

989680

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.513

High

394595

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

967553

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.493

High

436029

CO1A2
Collagen alpha-2(I) chain

1

1

High-throughput

0.489

High

571119

EGLN
Endoglin

1

1

High-throughput

0.489

High

790245

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

3

High-throughput

0.489

High

989670

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

6

High-throughput

0.489

High

989704

LAR4B
La-related protein 4B

1

12

High-throughput

0.489

High

989703

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

303188

HEXI1
Protein HEXIM1

1

8

High-throughput

0.479

High

668626

PML
Protein PML

1

11

High-throughput

0.479

High

683985

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

989705

REQU
Zinc finger protein ubi-d4

1

2

High-throughput

0.479

High

989712

RAB3I
Rab-3A-interacting protein

1

1

High-throughput

0.479

High

989736

CBY1
Protein chibby homolog 1

1

1

High-throughput

0.479

High

297968

FCSD2
F-BAR and double SH3 domains protein 2

1

2

High-throughput

0.470

High

989682

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

989695

NUTM1
NUT family member 1

1

0

High-throughput

0.460

High

989719

KATL1
Katanin p60 ATPase-containing subunit A-like 1

1

10

High-throughput

0.445

High

431212

CATB
Cathepsin B

1

1

High-throughput

0.437

High

989716

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.426

High

297859

SC24D
Protein transport protein Sec24D

1

7

Small-scale

0.417

High

989675

SC23A
Protein transport protein Sec23A

1

5

Small-scale

0.417

High

989685

DNLZ
DNL-type zinc finger protein

3

0

High-throughput

0.342

High

611558

CAH4
Carbonic anhydrase 4

2

0

High-throughput

0.318

High

989686

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

989701

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

989666

FP100
Fanconi anemia core complex-associated protein 100

1

0

High-throughput

0.279

Low

989713

METH
Methionine synthase

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024