HitPredict

Interactor 1: Q8IMX8 (Q8IMX8)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSm3

Interactor 2: Q9VRT7 (Q9VRT7)
U6 snRNA-associated Sm-like protein LSm5
Gene: BcDNA:RE60135

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005688 - U6 snRNP GO:0046540 - U4/U6 x U5 tri-snRNP complex GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Dm			1 91
+	Hs
		912210 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Hs
		911607 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Hs
		928048 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Hs
		539203 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Dm
		1367657 SMD2_DROME (1-96): 2.16e-27: 98.5: 30.30		Q9VRT7_DROME (1-91): 9.35e-33: 110: 100.00
+	Hs
		911614 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Hs
		538889 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Hs
		911610 SMD2_HUMAN (1-96): 1.26e-26: 96.6: 31.31		RUXE_HUMAN (7-85): 3.36e-27: 96.5: 25.30
+	Sp
		1378244 LSM3_SCHPO (10-99): 5.37e-30: 104: 60.00		LSM3_SCHPO (11-86): 2.5e-23: 86.9: 20.93
+	Hs
		912202 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		LSM7_HUMAN (19-85): 1.09e-14: 64.9: 26.39
+	Hs
		912020 LSM3_HUMAN (1-103): 4.31e-38: 125: 76.70		RUXG_HUMAN (19-84): 1.18e-13: 61.8: 22.73
+	Hs
		538892 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		LSM3_HUMAN (7-86): 4.38e-23: 86.5: 24.44
+	Hs
		539178 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		LSM7_HUMAN (19-85): 1.09e-14: 64.9: 26.39
+	Hs
		912026 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		RUXG_HUMAN (19-84): 1.18e-13: 61.8: 22.73
+	Hs
		538891 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		RUXG_HUMAN (19-84): 1.18e-13: 61.8: 22.73
+	Dm
		1367659 SMD2_DROME (1-96): 2.16e-27: 98.5: 30.30		RUXG_DROME (19-84): 1.53e-13: 61.5: 27.27
+	Hs
		68412 RSMN_HUMAN (24-103): 3.91e-27: 101: 21.43		RUXGL_HUMAN (19-84): 2.58e-12: 58.4: 22.73
+	Hs
		912023 SMD2_HUMAN (1-96): 1.26e-26: 96.6: 31.31		RUXG_HUMAN (19-84): 1.18e-13: 61.8: 22.73
+	Hs
		68400 RSMB_HUMAN (24-103): 1.27e-26: 99.7: 21.43		RUXGL_HUMAN (19-84): 2.58e-12: 58.4: 22.73
+	Hs
		68410 SMD2_HUMAN (1-96): 1.26e-26: 96.6: 31.31		RUXGL_HUMAN (19-84): 2.58e-12: 58.4: 22.73