Protein: ARL8B
ADP-ribosylation factor-like protein 8B (EC 3.6.5.2) (ADP-ribosylation factor-like protein 10C) (Novel small G protein indispensable for equal chromosome segregation 1)

Gene: ARL8B
Organism: Homo sapiens
Interactions: 202
UniProt ID: Q9NVJ2

Gene Ontology (top 5):
GO:0001778 - plasma membrane repair
GO:0002505 - antigen processing and presentation of polysaccharide antigen via MHC class II
GO:0002747 - antigen processing and presentation following phagocytosis
GO:0003924 - GTPase activity
GO:0003925 - G protein activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1384766

ARL8A
ADP-ribosylation factor-like protein 8A

4

17

High-throughput

0.892

High

1450649

PKHM1
Pleckstrin homology domain-containing family M member 1

2

12

Small-scale

0.815

High

1403357

RUFY1
RUN and FYVE domain-containing protein 1

2

17

High-throughput

0.806

High

1270827

RUFY3
Protein RUFY3

2

14

High-throughput

0.768

High

1367884

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

8

High-throughput

0.691

High

1450635

DP13A
DCC-interacting protein 13-alpha

1

9

High-throughput

0.691

High

1450647

LTOR2
Ragulator complex protein LAMTOR2

1

2

High-throughput

0.691

High

901608

RAB7A
Ras-related protein Rab-7a

4

18

Small-scale

0.686

High

1411421

CAB45
45 kDa calcium-binding protein

3

3

High-throughput

0.667

High

1450654

SRPRB
Signal recognition particle receptor subunit beta

3

18

High-throughput

0.667

High

1200957

SGO2
Shugoshin 2

3

0

High-throughput

0.638

High

1310003

PKHM2
Pleckstrin homology domain-containing family M member 2

1

12

High-throughput

0.618

High

1360185

RUFY2
RUN and FYVE domain-containing protein 2

1

14

High-throughput

0.618

High

1386717

AP2M1
AP-2 complex subunit mu

1

3

High-throughput

0.618

High

1450641

GAB2
GRB2-associated-binding protein 2

1

6

High-throughput

0.618

High

1164238

DGUOK
Deoxyguanosine kinase, mitochondrial

2

1

High-throughput

0.611

High

1371972

VPP1
V-type proton ATPase 116 kDa subunit a 1

2

6

High-throughput

0.611

High

1450626

KTU
Protein kintoun

2

2

High-throughput

0.611

High

1450639

VPS4A
Vacuolar protein sorting-associated protein 4A

2

12

High-throughput

0.611

High

1358062

CPLX3
Complexin-3

2

0

High-throughput

0.602

High

1314554

TM192
Transmembrane protein 192

2

2

Small-scale

0.601

High

1450633

CIDEB
Lipid transferase CIDEB

2

0

High-throughput

0.580

High

720638

GRPR
Gastrin-releasing peptide receptor

2

6

High-throughput

0.574

High

1413108

INP5K
Inositol polyphosphate 5-phosphatase K

1

9

Small-scale

0.573

High

1334091

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

2

1

High-throughput

0.558

High

1310966

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

11

High-throughput

0.553

High

1449795

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

1216533

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

20

High-throughput

0.553

High

1450652

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

3

High-throughput

0.553

High

137394

BT3A3
Butyrophilin subfamily 3 member A3

1

2

High-throughput

0.541

High

170544

RAB7L
Ras-related protein Rab-7L1

1

20

High-throughput

0.536

High

174120

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

11

High-throughput

0.536

High

189875

STX7
Syntaxin-7

1

12

High-throughput

0.536

High

247171

TBCD4
TBC1 domain family member 4

1

12

High-throughput

0.536

High

301820

ANXA9
Annexin A9

1

3

High-throughput

0.536

High

370791

FOS
Protein c-Fos

1

5

High-throughput

0.536

High

401571

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.536

High

540706

LAMP1
Lysosome-associated membrane glycoprotein 1

1

20

High-throughput

0.536

High

691474

1433T
14-3-3 protein theta

1

12

High-throughput

0.536

High

730285

1433B
14-3-3 protein beta/alpha

1

12

High-throughput

0.536

High

908054

VAMP7
Vesicle-associated membrane protein 7

1

16

High-throughput

0.536

High

966932

1433G
14-3-3 protein gamma

1

12

High-throughput

0.536

High

972053

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

990786

1433Z
14-3-3 protein zeta/delta

1

12

High-throughput

0.536

High

1023899

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.536

High

1049830

1433F
14-3-3 protein eta

1

12

High-throughput

0.536

High

1101056

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.536

High

1270539

MARK2
Serine/threonine-protein kinase MARK2

1

8

High-throughput

0.536

High

1286718

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

1

High-throughput

0.536

High

1330610

PLD5
Inactive phospholipase D5

1

1

High-throughput

0.536

High

1334990

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.536

High

1350320

RAE1E
Retinoic acid early transcript 1E

1

6

High-throughput

0.536

High

1357012

PDC6I
Programmed cell death 6-interacting protein

1

1

High-throughput

0.536

High

1359456

LMO7
LIM domain only protein 7

1

2

High-throughput

0.536

High

1380545

PIGT
GPI-anchor transamidase component PIGT

1

2

High-throughput

0.536

High

1400931

VPS35
Vacuolar protein sorting-associated protein 35

1

2

High-throughput

0.536

High

1417363

S26A6
Solute carrier family 26 member 6

1

4

High-throughput

0.536

High

1429711

KLC2
Kinesin light chain 2

1

1

High-throughput

0.536

High

1450628

SPG21
Maspardin

1

1

High-throughput

0.536

High

1450629

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

4

High-throughput

0.536

High

1450640

BAIP2
BAR/IMD domain-containing adapter protein 2

1

4

High-throughput

0.536

High

1450642

LAMP3
Lysosome-associated membrane glycoprotein 3

1

20

High-throughput

0.536

High

1450644

TPPC4
Trafficking protein particle complex subunit 4

1

2

High-throughput

0.536

High

1450646

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.536

High

1450650

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.536

High

1450653

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

1

High-throughput

0.536

High

179405

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.513

High

194478

P2RX6
P2X purinoceptor 6

1

0

High-throughput

0.513

High

829931

PMEL
Melanocyte protein PMEL

1

0

High-throughput

0.513

High

1212730

TMTC4
Protein O-mannosyl-transferase TMTC4

1

0

High-throughput

0.513

High

1239316

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.513

High

1292348

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.513

High

1336532

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.513

High

1387674

NXPE2
NXPE family member 2

1

0

High-throughput

0.513

High

1409693

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

1

0

High-throughput

0.513

High

1447993

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

1450630

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.513

High

1450631

VPS29
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.513

High

1450638

OAZ3
Ornithine decarboxylase antizyme 3

1

0

High-throughput

0.513

High

1450645

TPPC8
Trafficking protein particle complex subunit 8

1

0

High-throughput

0.513

High

423297

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

888820

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

3

Small-scale

0.501

High

958036

RAB14
Ras-related protein Rab-14

1

17

High-throughput

0.501

High

133881

FOXN3
Forkhead box protein N3

1

4

High-throughput

0.489

High

221972

FOXS1
Forkhead box protein S1

1

4

High-throughput

0.489

High

406931

MAS
Proto-oncogene Mas

1

6

High-throughput

0.489

High

488351

PPBI
Intestinal-type alkaline phosphatase

1

2

High-throughput

0.489

High

722857

SSR1
Somatostatin receptor type 1

1

6

High-throughput

0.489

High

1090117

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

6

High-throughput

0.489

High

1098947

KLRD1
Natural killer cells antigen CD94

1

6

High-throughput

0.489

High

1357161

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.489

High

1390893

ASIC4
Acid-sensing ion channel 4

1

2

High-throughput

0.489

High

1413993

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.489

High

1431375

TSN10
Tetraspanin-10

1

2

High-throughput

0.489

High

1449684

TB22B
TBC1 domain family member 22B

1

20

High-throughput

0.489

High

1450634

PHF11
PHD finger protein 11

1

2

High-throughput

0.489

High

1450637

CLC4A
C-type lectin domain family 4 member A

1

4

High-throughput

0.489

High

1450651

PCDGD
Protocadherin gamma-B1

1

3

High-throughput

0.489

High

125637

LEG9
Galectin-9

1

3

High-throughput

0.479

High

134455

EF2K
Eukaryotic elongation factor 2 kinase

1

2

High-throughput

0.479

High

178419

NPC1
NPC intracellular cholesterol transporter 1

1

5

High-throughput

0.479

High

178845

SCAM1
Secretory carrier-associated membrane protein 1

1

16

High-throughput

0.479

High

210612

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

1

High-throughput

0.479

High

243090

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.479

High

249205

DSCAM
Cell adhesion molecule DSCAM

1

5

High-throughput

0.479

High

280353

SC22B
Vesicle-trafficking protein SEC22b

1

12

High-throughput

0.479

High

318890

RHBT1
Rho-related BTB domain-containing protein 1

1

20

High-throughput

0.479

High

323002

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

2

High-throughput

0.479

High

331359

KI20A
Kinesin-like protein KIF20A

1

16

High-throughput

0.479

High

402424

GBA1
Lysosomal acid glucosylceramidase

1

1

High-throughput

0.479

High

431917

ITB1
Integrin beta-1

1

5

High-throughput

0.479

High

457736

TBB5
Tubulin beta chain

1

3

Small-scale

0.479

High

466488

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

508709

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

18

High-throughput

0.479

High

548620

MPRI
Cation-independent mannose-6-phosphate receptor

1

9

High-throughput

0.479

High

581323

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

583109

VATB1
V-type proton ATPase subunit B, kidney isoform

1

4

High-throughput

0.479

High

749147

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.479

High

800577

VATA
V-type proton ATPase catalytic subunit A

1

9

High-throughput

0.479

High

882186

TCPG
T-complex protein 1 subunit gamma

1

3

High-throughput

0.479

High

883340

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

8

High-throughput

0.479

High

895104

EMD
Emerin

1

3

High-throughput

0.479

High

898143

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

5

High-throughput

0.479

High

913995

RBM5
RNA-binding protein 5

1

6

High-throughput

0.479

High

922788

CCHL
Holocytochrome c-type synthase

1

2

High-throughput

0.479

High

930060

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.479

High

945535

SNX16
Sorting nexin-16

1

8

High-throughput

0.479

High

955663

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

962548

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

978346

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

1005152

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

1015838

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1032257

EXOSX
Exosome complex component 10

1

2

High-throughput

0.479

High

1062673

DHX9
ATP-dependent RNA helicase A

1

1

High-throughput

0.479

High

1090194

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

16

High-throughput

0.479

High

1117312

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

3

High-throughput

0.479

High

1122957

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

3

High-throughput

0.479

High

1131840

LBR
Delta(14)-sterol reductase LBR

1

3

High-throughput

0.479

High

1134066

ZN638
Zinc finger protein 638

1

1

High-throughput

0.479

High

1152264

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.479

High

1154765

VAMP3
Vesicle-associated membrane protein 3

1

17

High-throughput

0.479

High

1155824

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

High-throughput

0.479

High

1159869

OCLN
Occludin

1

7

High-throughput

0.479

High

1196329

GRAP1
GRIP1-associated protein 1

1

5

High-throughput

0.479

High

1204038

FILA2
Filaggrin-2

1

4

High-throughput

0.479

High

1209717

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

13

High-throughput

0.479

High

1213198

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

1

High-throughput

0.479

High

1233526

LTOR1
Ragulator complex protein LAMTOR1

1

9

High-throughput

0.479

High

1241124

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

2

High-throughput

0.479

High

1247016

RICTR
Rapamycin-insensitive companion of mTOR

1

6

High-throughput

0.479

High

1255775

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

1257954

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

3

High-throughput

0.479

High

1275713

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

3

High-throughput

0.479

High

1323168

CCAR2
Cell cycle and apoptosis regulator protein 2

1

3

High-throughput

0.479

High

1330949

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

1334593

RN149
E3 ubiquitin-protein ligase RNF149

1

13

High-throughput

0.479

High

1355903

DUS19
Dual specificity protein phosphatase 19

1

13

High-throughput

0.479

High

1385445

SYTL4
Synaptotagmin-like protein 4

1

5

High-throughput

0.479

High

1401769

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

8

High-throughput

0.479

High

1408295

DUS9
Dual specificity protein phosphatase 9

1

11

High-throughput

0.479

High

1430215

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

5

Small-scale

0.479

High

1433533

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1436702

GORS2
Golgi reassembly-stacking protein 2

1

6

High-throughput

0.479

High

1447685

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

7

High-throughput

0.479

High

1450636

MYO6
Unconventional myosin-VI

1

6

High-throughput

0.479

High

1450648

MAN1
Inner nuclear membrane protein Man1

1

6

High-throughput

0.479

High

1450655

TACC3
Transforming acidic coiled-coil-containing protein 3

1

8

High-throughput

0.479

High

1450656

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

9

High-throughput

0.479

High

229089

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.458

High

717236

KCY
UMP-CMP kinase

1

0

High-throughput

0.458

High

1419679

PUS3
tRNA pseudouridine(38/39) synthase

1

0

High-throughput

0.458

High

1429860

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1432982

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

1446967

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1450632

LTOR3
Ragulator complex protein LAMTOR3

1

0

High-throughput

0.458

High

956017

RAB8A
Ras-related protein Rab-8A

1

18

Small-scale

0.445

High

1273815

NIPA1
Magnesium transporter NIPA1

1

2

High-throughput

0.445

High

1288929

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

6

High-throughput

0.445

High

1417640

S46A2
Solute carrier family 46 member 2

1

11

High-throughput

0.445

High

1450643

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.445

High

106729

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

353584

AGR2
Anterior gradient protein 2 homolog

1

7

High-throughput

0.437

High

474328

NFIC
Nuclear factor 1 C-type

1

1

High-throughput

0.437

High

589836

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

696656

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.437

High

769323

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.437

High

1111727

STIM1
Stromal interaction molecule 1

1

2

High-throughput

0.437

High

1231291

BLT3A
Bridge-like lipid transfer protein family member 3A

1

11

High-throughput

0.437

High

1278128

MAVS
Mitochondrial antiviral-signaling protein

1

5

High-throughput

0.437

High

1411496

OVOL2
Transcription factor Ovo-like 2

1

3

Small-scale

0.437

High

1429369

SPRTN
DNA-dependent metalloprotease SPRTN

1

6

High-throughput

0.437

High

344337

PTBP3
Polypyrimidine tract-binding protein 3

1

3

High-throughput

0.407

High

399397

MIS
Muellerian-inhibiting factor

1

0

High-throughput

0.282

High

939832

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

High-throughput

0.282

High

749408

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

1332624

I17RC
Interleukin-17 receptor C

1

0

High-throughput

0.279

Low

1385207

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1438714

CRLF2
Cytokine receptor-like factor 2

1

0

High-throughput

0.279

Low

1450627

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.279

Low

1273165

KDM3B
Lysine-specific demethylase 3B

1

0

High-throughput

0.249

Low

1438925

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.249

Low

211688

LEU1
Leukemia-associated protein 1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025