Interactor 1: TR10A (O00220)
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)
Gene: TNFRSF10A

Interactor 2: CD70 (P32970)
CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70)
Gene: CD70

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~TNFR_c6
Common GO terms GO:0002020 - protease binding
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0097191 - extrinsic apoptotic signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 468
Hs

1 193
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024