Protein: ZN668
Zinc finger protein 668

Gene: ZN668, ZNF668
Organism: Homo sapiens
Interactions: 226
UniProt ID: Q96K58

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1395687

ZN512
Zinc finger protein 512

2

13

High-throughput

0.811

High

585085

ZN250
Zinc finger protein 250

2

5

High-throughput

0.783

High

892418

ZN165
Zinc finger protein 165

2

18

High-throughput

0.783

High

1186356

ZN792
Zinc finger protein 792

2

7

High-throughput

0.783

High

174446

ZN646
Zinc finger protein 646

1

8

High-throughput

0.691

High

208881

ZBT24
Zinc finger and BTB domain-containing protein 24

1

16

High-throughput

0.691

High

255929

Z354A
Zinc finger protein 354A

1

4

High-throughput

0.691

High

340525

ZBT11
Zinc finger and BTB domain-containing protein 11

1

8

High-throughput

0.691

High

886560

CTCF
Transcriptional repressor CTCF

1

10

High-throughput

0.691

High

1006631

SRPK2
SRSF protein kinase 2

1

4

High-throughput

0.691

High

1153657

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

12

High-throughput

0.691

High

1234777

ZN770
Zinc finger protein 770

1

6

High-throughput

0.691

High

1252655

ZN574
Zinc finger protein 574

1

4

High-throughput

0.691

High

1281441

ZN467
Zinc finger protein 467

1

15

High-throughput

0.691

High

1333136

ZFP62
Zinc finger protein 62 homolog

1

2

High-throughput

0.691

High

1395689

ZN317
Zinc finger protein 317

1

3

High-throughput

0.691

High

1395692

ZN184
Zinc finger protein 184

1

3

High-throughput

0.691

High

1395727

ZNF70
Zinc finger protein 70

1

5

High-throughput

0.691

High

1395728

ZN629
Zinc finger protein 629

1

3

High-throughput

0.691

High

1395729

ZBT47
Zinc finger and BTB domain-containing protein 47

1

19

High-throughput

0.691

High

1395736

ZN777
Zinc finger protein 777

1

13

High-throughput

0.691

High

1037315

H11
Histone H1.1

3

10

High-throughput

0.667

High

447321

NPM
Nucleophosmin

3

9

Small-scale

0.656

High

1393146

PRR11
Proline-rich protein 11

3

0

High-throughput

0.638

High

521861

H14
Histone H1.4

2

10

High-throughput

0.628

High

612735

RL7
Large ribosomal subunit protein uL30

2

2

High-throughput

0.628

High

649393

H1T
Histone H1t

2

10

High-throughput

0.628

High

984496

RL30
Large ribosomal subunit protein eL30

2

2

High-throughput

0.628

High

1361735

DGCR8
Microprocessor complex subunit DGCR8

2

2

High-throughput

0.628

High

898765

RL14
Large ribosomal subunit protein eL14

3

3

High-throughput

0.609

High

687284

HMGB2
High mobility group protein B2

2

3

Small-scale

0.603

High

969370

RS8
Small ribosomal subunit protein eS8

2

0

High-throughput

0.585

High

1359883

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

0

High-throughput

0.580

High

1085807

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.578

High

208341

RRP8
Ribosomal RNA-processing protein 8

2

2

High-throughput

0.574

High

182344

WDR46
WD repeat-containing protein 46

2

5

High-throughput

0.558

High

288734

NPM3
Nucleoplasmin-3

2

9

High-throughput

0.549

High

290679

SURF6
Surfeit locus protein 6

2

2

High-throughput

0.549

High

1112129

KRR1
KRR1 small subunit processome component homolog

2

4

High-throughput

0.549

High

191750

MAGB2
Melanoma-associated antigen B2

1

2

High-throughput

0.536

High

215849

P52K
52 kDa repressor of the inhibitor of the protein kinase

1

2

High-throughput

0.536

High

287092

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

18

High-throughput

0.536

High

338934

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.536

High

428912

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.536

High

591789

H2AX
Histone H2AX

1

2

High-throughput

0.536

High

595845

H13
Histone H1.3

1

10

High-throughput

0.536

High

615923

RL17
Large ribosomal subunit protein uL22

1

4

High-throughput

0.536

High

658345

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.536

High

686344

RL13
Large ribosomal subunit protein eL13

1

4

High-throughput

0.536

High

785364

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.536

High

788746

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

824287

RL13A
Large ribosomal subunit protein uL13

1

4

High-throughput

0.536

High

846421

MATR3
Matrin-3

1

1

High-throughput

0.536

High

855174

NOP2
28S rRNA

1

4

High-throughput

0.536

High

860317

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.536

High

975866

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.536

High

978662

RL23A
Large ribosomal subunit protein uL23

1

3

High-throughput

0.536

High

979141

RS6
Small ribosomal subunit protein eS6

1

2

High-throughput

0.536

High

982775

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.536

High

985285

RL10A
Large ribosomal subunit protein uL1

1

5

High-throughput

0.536

High

994727

YBOX1
Y-box-binding protein 1

1

9

High-throughput

0.536

High

1009287

PRR3
Proline-rich protein 3

1

2

High-throughput

0.536

High

1025740

PURA
Transcriptional activator protein Pur-alpha

1

8

High-throughput

0.536

High

1047697

NOTC2
Neurogenic locus notch homolog protein 2

1

7

High-throughput

0.536

High

1061098

SRSF1
Serine/arginine-rich splicing factor 1

1

11

High-throughput

0.536

High

1089803

ILF3
Interleukin enhancer-binding factor 3

1

8

High-throughput

0.536

High

1098270

DDX10
Probable ATP-dependent RNA helicase DDX10

1

2

High-throughput

0.536

High

1117636

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.536

High

1134031

ZN638
Zinc finger protein 638

1

1

High-throughput

0.536

High

1146520

TTF1
Transcription termination factor 1

1

1

High-throughput

0.536

High

1178072

RN151
RING finger protein 151

1

7

High-throughput

0.536

High

1179703

LIN41
E3 ubiquitin-protein ligase TRIM71

1

20

High-throughput

0.536

High

1219422

TUT7
Terminal uridylyltransferase 7

1

1

High-throughput

0.536

High

1219736

ZMYM4
Zinc finger MYM-type protein 4

1

5

High-throughput

0.536

High

1240477

DHX57
Putative ATP-dependent RNA helicase DHX57

1

4

High-throughput

0.536

High

1243583

RSBNL
Lysine-specific demethylase RSBN1L

1

1

High-throughput

0.536

High

1245480

CC137
Coiled-coil domain-containing protein 137

1

3

High-throughput

0.536

High

1260400

H1FNT
Testis-specific H1 histone

1

2

High-throughput

0.536

High

1271503

DHX30
ATP-dependent RNA helicase DHX30

1

3

High-throughput

0.536

High

1307297

H2A2B
Histone H2A type 2-B

1

2

High-throughput

0.536

High

1331033

DDX51
ATP-dependent RNA helicase DDX51

1

4

High-throughput

0.536

High

1351009

DDX54
ATP-dependent RNA helicase DDX54

1

2

High-throughput

0.536

High

1390577

NEIL1
Endonuclease 8-like 1

1

3

High-throughput

0.536

High

1395691

KIF2C
Kinesin-like protein KIF2C

1

2

High-throughput

0.536

High

1395693

RBM4B
RNA-binding protein 4B

1

4

High-throughput

0.536

High

1395695

MBB1A
Myb-binding protein 1A

1

1

High-throughput

0.536

High

1395697

RBM4
RNA-binding protein 4

1

4

High-throughput

0.536

High

1395699

GTPB4
GTP-binding protein 4

1

1

High-throughput

0.536

High

1395700

REXO4
RNA exonuclease 4

1

2

High-throughput

0.536

High

1395703

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

3

High-throughput

0.536

High

1395708

DDX31
ATP-dependent DNA helicase DDX31

1

2

High-throughput

0.536

High

1395710

LN28A
Protein lin-28 homolog A

1

11

High-throughput

0.536

High

1395712

SSF1
Suppressor of SWI4 1 homolog

1

3

High-throughput

0.536

High

1395714

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

2

High-throughput

0.536

High

1395715

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

2

High-throughput

0.536

High

1395720

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.536

High

1395723

DDX56
Probable ATP-dependent RNA helicase DDX56

1

2

High-throughput

0.536

High

1395724

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.536

High

1395734

PURG
Purine-rich element-binding protein gamma

1

8

High-throughput

0.536

High

1395735

ZN346
Zinc finger protein 346

1

2

High-throughput

0.536

High

1395738

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

1395742

YBOX2
Y-box-binding protein 2

1

9

High-throughput

0.536

High

96743

E9PAV9
G patch domain-containing protein 4

2

11

High-throughput

0.533

High

183056

NKRF
NF-kappa-B-repressing factor

1

0

High-throughput

0.513

High

355581

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

High-throughput

0.513

High

586832

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

620525

NUCL
Nucleolin

1

0

High-throughput

0.513

High

770042

RFC1
Replication factor C subunit 1

1

0

High-throughput

0.513

High

959910

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.513

High

973267

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

982517

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.513

High

1039337

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.513

High

1043727

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.513

High

1057853

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

1130386

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.513

High

1132628

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.513

High

1194285

LARP7
La-related protein 7

1

0

High-throughput

0.513

High

1239138

NEPRO
Nucleolus and neural progenitor protein

1

0

High-throughput

0.513

High

1275613

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.513

High

1316434

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.513

High

1392095

TOE1
Target of EGR1 protein 1

1

0

High-throughput

0.513

High

1395685

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

1395690

F111A
Serine protease FAM111A

1

0

High-throughput

0.513

High

1395702

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

1395711

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.513

High

1395713

SAS10
Something about silencing protein 10

1

0

High-throughput

0.513

High

1395721

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.513

High

1395722

AATF
Protein AATF

1

0

High-throughput

0.513

High

1395743

RBMX2
RNA-binding motif protein, X-linked 2

1

0

High-throughput

0.513

High

301169

RL1D1
Ribosomal L1 domain-containing protein 1

1

5

High-throughput

0.489

High

346199

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

18

High-throughput

0.489

High

657286

KALM
Anosmin-1

1

7

High-throughput

0.489

High

716938

RL12
Large ribosomal subunit protein uL11

1

1

High-throughput

0.489

High

809785

RS19
Small ribosomal subunit protein eS19

1

3

High-throughput

0.489

High

841425

RBM34
RNA-binding protein 34

1

1

High-throughput

0.489

High

860888

RS10
Small ribosomal subunit protein eS10

1

4

High-throughput

0.489

High

970042

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.489

High

984907

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.489

High

985816

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.489

High

1016166

RL19
Large ribosomal subunit protein eL19

1

4

High-throughput

0.489

High

1099205

SRSF5
Serine/arginine-rich splicing factor 5

1

14

High-throughput

0.489

High

1099478

SRSF6
Serine/arginine-rich splicing factor 6

1

16

High-throughput

0.489

High

1148141

PUM3
Pumilio homolog 3

1

1

High-throughput

0.489

High

1151176

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.489

High

1168554

KNOP1
Lysine-rich nucleolar protein 1

1

1

High-throughput

0.489

High

1290022

PNM8A
Paraneoplastic antigen-like protein 8A

1

2

High-throughput

0.489

High

1294416

SPAS2
Spermatogenesis-associated serine-rich protein 2

1

1

High-throughput

0.489

High

1313913

DHX37
Probable ATP-dependent RNA helicase DHX37

1

3

High-throughput

0.489

High

1314204

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

1

High-throughput

0.489

High

1336617

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.489

High

1356014

NOC3L
Nucleolar complex protein 3 homolog

1

1

High-throughput

0.489

High

1360231

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

1

High-throughput

0.489

High

1389489

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

2

High-throughput

0.489

High

1391247

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.489

High

1392208

DDX27
Probable ATP-dependent RNA helicase DDX27

1

1

High-throughput

0.489

High

1395688

CC140
Coiled-coil domain-containing protein 140

1

2

High-throughput

0.489

High

1395694

DDX50
ATP-dependent RNA helicase DDX50

1

2

High-throughput

0.489

High

1395701

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.489

High

1395705

YTDC2
3'-5' RNA helicase YTHDC2

1

3

High-throughput

0.489

High

1395709

RPF1
Ribosome production factor 1

1

1

High-throughput

0.489

High

1395716

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

18

High-throughput

0.489

High

1395717

SPS2L
SPATS2-like protein

1

1

High-throughput

0.489

High

1395718

DDX18
ATP-dependent RNA helicase DDX18

1

3

High-throughput

0.489

High

1395745

RL36
Large ribosomal subunit protein eL36

1

8

High-throughput

0.489

High

1395746

RBM19
Probable RNA-binding protein 19

1

2

High-throughput

0.489

High

822819

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.481

High

194301

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

406512

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

414416

P53
Cellular tumor antigen p53

1

5

Small-scale

0.479

High

504952

H2AB2
Histone H2A-Bbd type 2/3

1

4

High-throughput

0.479

High

810291

RL3
Large ribosomal subunit protein uL3

1

4

High-throughput

0.479

High

980150

H4
Histone H4

1

2

High-throughput

0.479

High

1004979

RNF4
E3 ubiquitin-protein ligase RNF4

1

11

High-throughput

0.479

High

1028342

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

1114012

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1215772

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1367031

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

1371242

KAT5
Histone acetyltransferase KAT5

1

1

Small-scale

0.479

High

1395704

VCX1
Variable charge X-linked protein 1

1

0

High-throughput

0.460

High

693910

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

1395725

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.458

High

106472

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

1395737

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

1395739

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.437

High

1395726

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.426

High

69966

A8KAG1
G patch domain-containing protein 4

1

11

High-throughput

0.407

High

72798

B0UZZ8
WD repeat-containing protein 46

1

5

High-throughput

0.407

High

1212357

GPTC4
G patch domain-containing protein 4

1

11

High-throughput

0.407

High

1395730

NOL12
Nucleolar protein 12

3

0

High-throughput

0.347

High

986148

RL8
Large ribosomal subunit protein uL2

2

0

High-throughput

0.318

High

1118962

BYST
Bystin

2

0

High-throughput

0.316

High

61979

GTPBA
GTP-binding protein 10

1

0

High-throughput

0.279

Low

134360

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

140621

MPP10
U3 small nucleolar ribonucleoprotein protein MPP10

1

0

High-throughput

0.279

Low

244390

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.279

Low

338169

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.279

Low

428209

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.279

Low

428478

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.279

Low

860586

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.279

Low

907685

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

1011351

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.279

Low

1037592

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.279

Low

1130956

BMS1
Ribosome biogenesis protein BMS1 homolog

1

0

High-throughput

0.279

Low

1139993

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.279

Low

1150343

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

1

0

High-throughput

0.279

Low

1193363

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.279

Low

1203890

NOM1
Nucleolar MIF4G domain-containing protein 1

1

0

High-throughput

0.279

Low

1206753

RRP12
RRP12-like protein

1

0

High-throughput

0.279

Low

1241027

L2GL2
LLGL scribble cell polarity complex component 2

1

0

High-throughput

0.279

Low

1278688

KI21A
Kinesin-like protein KIF21A

1

0

High-throughput

0.279

Low

1287768

NOP9
Nucleolar protein 9

1

0

High-throughput

0.279

Low

1311593

SUGP2
SURP and G-patch domain-containing protein 2

1

0

High-throughput

0.279

Low

1350805

RS4Y2
Small ribosomal subunit protein eS4, Y isoform 2

1

0

High-throughput

0.279

Low

1395696

CHOLN
Protein cholesin

1

0

High-throughput

0.279

Low

1395698

MAK16
Protein MAK16 homolog

1

0

High-throughput

0.279

Low

1395706

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.279

Low

1395707

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.279

Low

1395719

PK1IP
p21-activated protein kinase-interacting protein 1

1

0

High-throughput

0.279

Low

1395731

RLP24
Probable ribosome biogenesis protein RLP24

1

0

High-throughput

0.279

Low

1395732

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.279

Low

1395733

IL17B
Interleukin-17B

1

0

High-throughput

0.279

Low

1395740

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

0

High-throughput

0.279

Low

1395741

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.279

Low

1395744

NOP16
Nucleolar protein 16

1

0

High-throughput

0.279

Low

652665

GNLY
Granulysin

1

0

High-throughput

0.232

Low

1395686

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025