HitPredict

Interactor 1: TR10A (O00220)
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)
Gene: TNFRSF10A

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 468 Hs			1 192
+	Hs
		121438 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		121436 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		121534 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		121464 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		121472 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		121466 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		121467 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		121431 TR10A_HUMAN (1-468): 1.13e-164: 474: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		154338 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		154305 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		154300 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		154414 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		154332 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		154343 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		154333 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		154335 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		154295 TR10B_HUMAN (60-466): 1.42e-110: 335: 51.91		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		584368 TNR1A_HUMAN (100-448): 7e-64: 215: 18.21		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		584359 TNR1A_HUMAN (100-448): 7e-64: 215: 18.21		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436154 TNR1A_HUMAN (100-448): 7e-64: 215: 18.21		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45