HitPredict

Interactor 1: Q8IR26 (Q8IR26)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: sordd2

Interactor 2: Q9W418 (Q9W418)
GH17761p (Ubiquitin-5E, isoform A) (Ubiquitin-5E, isoform B)
Gene: Ubi-p5E

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 283 Dm			1 534
+	Xl
		1140135 Q5XGX4_XENLA (90-275): 2.25e-54: 176: 48.66		Q7SY79_XENLA (1-457): 0: 565: 99.78
+	Xl
		1186351 NF7B_XENLA (47-217): 1.5e-28: 116: 12.99		Q7SY79_XENLA (1-457): 0: 565: 99.78
+	Dm
		1215070 Q8IR26_DROME (1-283): 1.12e-84: 256: 100.00		R9PY16_DROME (305-532): 5.11e-79: 251: 90.79
+	Dm
		1375478 Q9VXP1_DROME (1-274): 4.03e-80: 245: 91.27		R9PY16_DROME (305-532): 5.11e-79: 251: 90.79
+	At
		1092004 SM3L1_ARATH (106-197): 9.24e-15: 76.1: 27.17		UBQ3_ARATH (77-381): 3.27e-122: 362: 95.74
+	Hs
		476198 RN185_HUMAN (92-275): 1.31e-51: 169: 48.39		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		476274 RNF5_HUMAN (103-257): 1.34e-47: 158: 50.97		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Xl
		1140130 Q5XGX4_XENLA (90-275): 2.25e-54: 176: 48.66		Q6GMC1_XENLA (381-458): 1.34e-41: 148: 97.44
+	Hs
		924117 RN185_HUMAN (92-275): 1.31e-51: 169: 48.39		RS27A_HUMAN (381-458): 1.34e-41: 148: 97.44
+	Hs
		476484 BFAR_HUMAN (92-283): 7.21e-32: 124: 16.06		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		475680 TRI26_HUMAN (118-265): 7.51e-27: 111: 20.38		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Mm
		476948 RN185_MOUSE (92-275): 2.67e-53: 173: 48.39		UBC_MOUSE (1-108): 3.81e-30: 127: 90.74
+	Hs
		475759 HLTF_HUMAN (89-210): 2.82e-25: 107: 21.31		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		475137 RN185_HUMAN (92-275): 1.31e-51: 169: 48.39		UBB_HUMAN (1-77): 5.2e-26: 107: 98.70
+	Hs
		476078 COP1_HUMAN (114-178): 3.02e-17: 83.4: 32.31		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		475431 BRCA1_HUMAN (124-174): 4.47e-16: 80.3: 35.29		UBC_HUMAN (1-153): 1.26e-52: 191: 99.35
+	Hs
		475134 TRI11_HUMAN (111-216): 8.49e-30: 118: 24.53		UBB_HUMAN (1-77): 5.2e-26: 107: 98.70
+	Sc
		477303 SLX8_YEAST (11-175): 7.86e-29: 112: 26.19		UBI4P_YEAST (1-77): 3.08e-23: 103: 94.81
+	Mm
		476705 BRCA1_MOUSE (124-174): 6.48e-16: 79.9: 35.29		UBC_MOUSE (1-108): 3.81e-30: 127: 90.74
+	Hs
		474945 BRCA1_HUMAN (124-174): 4.47e-16: 80.3: 35.29		UBB_HUMAN (1-77): 5.2e-26: 107: 98.70