Interactor 1: CASP8 (Q8IRY7)
Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
Gene: Dredd

Interactor 2: Q9U8R4 (Q9U8R4)
Apaf-1/CED-4-related caspase activator Dapaf-1S (Death-associated APAF1-related killer, isoform A)
Gene: Dark

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 10934188, unassigned4
Identification Methods affinity chromatography technology, experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006915 - apoptotic process
GO:0007291 - sperm individualization
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 494
Dm

1 531
+ Dm
+ Dm

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Last updated: 15 Jul 2024