Protein: DDX55
ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55)

Gene: DDX55
Organism: Homo sapiens
Interactions: 184
UniProt ID: Q8NHQ9

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1340472

NOL12
Nucleolar protein 12

4

2

High-throughput

0.892

High

346091

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

20

High-throughput

0.754

High

287057

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.691

High

1340456

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

20

High-throughput

0.691

High

1340468

DDX56
Probable ATP-dependent RNA helicase DDX56

1

19

High-throughput

0.691

High

1340487

RL36
Large ribosomal subunit protein eL36

1

7

High-throughput

0.691

High

1327421

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.656

High

521820

H14
Histone H1.4

2

13

High-throughput

0.628

High

1340440

WDR89
WD repeat-containing protein 89

1

20

High-throughput

0.618

High

1008806

RED1
Double-stranded RNA-specific editase 1

1

20

High-throughput

0.618

High

1088462

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.618

High

1132841

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.618

High

1227095

A16L1
Autophagy-related protein 16-1

1

18

High-throughput

0.618

High

1338855

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.618

High

1340445

TTC1
Tetratricopeptide repeat protein 1

1

2

High-throughput

0.618

High

1340452

DDX23
Probable ATP-dependent RNA helicase DDX23

1

18

High-throughput

0.618

High

141011

NOP56
Nucleolar protein 56

2

15

High-throughput

0.611

High

422659

A4
Amyloid-beta precursor protein

2

4

High-throughput

0.602

High

658289

RS3
Small ribosomal subunit protein uS3

2

9

High-throughput

0.601

High

809738

RS19
Small ribosomal subunit protein eS19

2

12

High-throughput

0.601

High

860847

RS10
Small ribosomal subunit protein eS10

2

9

High-throughput

0.601

High

911314

IMA5
Importin subunit alpha-5

2

5

High-throughput

0.601

High

969319

RS8
Small ribosomal subunit protein eS8

2

9

High-throughput

0.601

High

1016116

RL19
Large ribosomal subunit protein eL19

2

7

High-throughput

0.601

High

1112098

KRR1
KRR1 small subunit processome component homolog

2

9

High-throughput

0.601

High

1117608

NOG2
Nucleolar GTP-binding protein 2

2

19

High-throughput

0.601

High

1340483

YBOX2
Y-box-binding protein 2

2

20

High-throughput

0.601

High

979075

RS6
Small ribosomal subunit protein eS6

2

12

High-throughput

0.584

High

980941

H2B1C
Histone H2B type 1-C/E/F/G/I

2

8

High-throughput

0.584

High

1340464

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

182333

WDR46
WD repeat-containing protein 46

1

20

High-throughput

0.575

High

1241010

L2GL2
LLGL scribble cell polarity complex component 2

1

10

High-throughput

0.575

High

935426

FGF8
Fibroblast growth factor 8

2

12

High-throughput

0.574

High

950589

KR108
Keratin-associated protein 10-8

1

1

High-throughput

0.573

High

396557

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

810232

RL3
Large ribosomal subunit protein uL3

2

8

High-throughput

0.571

High

1340479

RL26L
Ribosomal protein uL24-like

2

13

High-throughput

0.571

High

1254734

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.553

High

1340475

HECD1
E3 ubiquitin-protein ligase HECTD1

1

20

High-throughput

0.553

High

191716

MAGB2
Melanoma-associated antigen B2

2

9

High-throughput

0.549

High

244380

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

3

High-throughput

0.536

High

324996

HEXI1
Protein HEXIM1

1

5

High-throughput

0.536

High

447239

NPM
Nucleophosmin

1

10

High-throughput

0.536

High

686290

RL13
Large ribosomal subunit protein eL13

1

11

High-throughput

0.536

High

824245

RL13A
Large ribosomal subunit protein uL13

1

16

High-throughput

0.536

High

859912

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.536

High

960806

RL15
Large ribosomal subunit protein eL15

1

5

High-throughput

0.536

High

969985

RS16
Small ribosomal subunit protein uS9

1

8

High-throughput

0.536

High

978618

RL23A
Large ribosomal subunit protein uL23

1

10

High-throughput

0.536

High

1008637

MAP1A
Microtubule-associated protein 1A

1

6

High-throughput

0.536

High

1012221

RT11
Small ribosomal subunit protein uS11m

1

11

High-throughput

0.536

High

1032369

OTUD4
OTU domain-containing protein 4

1

4

High-throughput

0.536

High

1099446

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

1144087

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

1148735

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

9

High-throughput

0.536

High

1219413

TUT7
Terminal uridylyltransferase 7

1

4

High-throughput

0.536

High

1252471

LN28B
Protein lin-28 homolog B

1

20

High-throughput

0.536

High

1280991

PXK
PX domain-containing protein kinase-like protein

1

7

High-throughput

0.536

High

1291078

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

15

High-throughput

0.536

High

1340431

CTCFL
Transcriptional repressor CTCFL

1

4

High-throughput

0.536

High

1340433

DC2I1
Cytoplasmic dynein 2 intermediate chain 1

1

14

High-throughput

0.536

High

1340435

FGF13
Fibroblast growth factor 13

1

12

High-throughput

0.536

High

1340436

RMXL1
RNA binding motif protein, X-linked-like-1

1

19

High-throughput

0.536

High

1340439

NEIL1
Endonuclease 8-like 1

1

3

High-throughput

0.536

High

1340444

MTMR9
Myotubularin-related protein 9

1

2

High-throughput

0.536

High

1340447

AKAP9
A-kinase anchor protein 9

1

12

High-throughput

0.536

High

1340449

LLPH
Protein LLP homolog

1

1

High-throughput

0.536

High

1340450

UTP23
rRNA-processing protein UTP23 homolog

1

5

High-throughput

0.536

High

1340458

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.536

High

1340465

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

3

High-throughput

0.536

High

1340467

MTMRA
Myotubularin-related protein 10

1

2

High-throughput

0.536

High

1340476

ABT1
Activator of basal transcription 1

1

5

High-throughput

0.536

High

1340478

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

2

High-throughput

0.536

High

1340480

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

2

High-throughput

0.536

High

1340481

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

2

High-throughput

0.536

High

1340484

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

2

High-throughput

0.536

High

249638

SNX3
Sorting nexin-3

1

0

High-throughput

0.513

High

585807

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

0

High-throughput

0.513

High

1218816

FOCAD
Focadhesin

1

0

High-throughput

0.513

High

1307693

CRLF3
Cytokine receptor-like factor 3

1

0

High-throughput

0.513

High

1340437

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

1340438

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.513

High

1340460

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.513

High

1340462

AVEN
Cell death regulator Aven

1

0

High-throughput

0.513

High

1340485

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.513

High

1340489

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.513

High

502441

H2A1
Histone H2A type 1

1

10

High-throughput

0.489

High

657271

KALM
Anosmin-1

1

4

High-throughput

0.489

High

1127436

FGFP1
Fibroblast growth factor-binding protein 1

1

3

High-throughput

0.489

High

1281425

ZN467
Zinc finger protein 467

1

1

High-throughput

0.489

High

1340443

LENG8
Leukocyte receptor cluster member 8

1

3

High-throughput

0.489

High

129268

MEN1
Menin

1

7

High-throughput

0.479

High

191007

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

218507

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

272331

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.479

High

319924

UFL1
E3 UFM1-protein ligase 1

1

5

High-throughput

0.479

High

372631

MYC
Myc proto-oncogene protein

1

17

High-throughput

0.479

High

406411

MYCN
N-myc proto-oncogene protein

1

17

High-throughput

0.479

High

412285

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

461729

HS90A
Heat shock protein HSP 90-alpha

1

10

High-throughput

0.479

High

463663

LYN
Tyrosine-protein kinase Lyn

1

8

High-throughput

0.479

High

487550

PARP1
Poly [ADP-ribose] polymerase 1

1

11

High-throughput

0.479

High

542121

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.479

High

589212

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

643939

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

9

High-throughput

0.479

High

693855

RL10
Large ribosomal subunit protein uL16

1

11

High-throughput

0.479

High

695995

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

768693

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

883620

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

904947

MECP2
Methyl-CpG-binding protein 2

1

13

High-throughput

0.479

High

937829

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

941210

IF6
Eukaryotic translation initiation factor 6

1

4

High-throughput

0.479

High

982742

RS24
Small ribosomal subunit protein eS24

1

6

High-throughput

0.479

High

984860

RL31
Large ribosomal subunit protein eL31

1

15

High-throughput

0.479

High

998570

H31
Histone H3.1

1

20

High-throughput

0.479

High

1017041

H33
Histone H3.3

1

20

High-throughput

0.479

High

1024711

VIGLN
Vigilin

1

14

High-throughput

0.479

High

1045546

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

1067522

EP300
Histone acetyltransferase p300

1

15

High-throughput

0.479

High

1087461

GRSF1
G-rich sequence factor 1

1

20

High-throughput

0.479

High

1137869

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1138415

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

11

High-throughput

0.479

High

1140588

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1161559

IF16
Gamma-interferon-inducible protein 16

1

11

High-throughput

0.479

High

1207410

HABP4
Intracellular hyaluronan-binding protein 4

1

5

High-throughput

0.479

High

1215725

RC3H1
Roquin-1

1

9

High-throughput

0.479

High

1281563

SLN11
Schlafen family member 11

1

3

High-throughput

0.479

High

1290602

ZCH18
Zinc finger CCCH domain-containing protein 18

1

11

High-throughput

0.479

High

1329755

SIR6
NAD-dependent protein deacylase sirtuin-6

1

7

High-throughput

0.479

High

1334672

SERB1
SERPINE1 mRNA-binding protein 1

1

5

High-throughput

0.479

High

1340432

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

6

High-throughput

0.479

High

1340434

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1340441

DDRGK
DDRGK domain-containing protein 1

1

8

High-throughput

0.479

High

1340448

RIOK1
Serine/threonine-protein kinase RIO1

1

10

High-throughput

0.479

High

1340453

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

18

High-throughput

0.479

High

1340459

RC3H2
Roquin-2

1

14

High-throughput

0.479

High

1340461

BRD7
Bromodomain-containing protein 7

1

18

High-throughput

0.479

High

1340463

ANLN
Anillin

1

6

High-throughput

0.479

High

1340469

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1340470

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

11

High-throughput

0.479

High

1340471

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1340477

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.479

High

1340486

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

828668

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.458

High

1340454

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1340455

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

66067

RP1BL
Ras-related protein Rap-1b-like protein

1

7

High-throughput

0.445

High

208317

RRP8
Ribosomal RNA-processing protein 8

1

4

High-throughput

0.445

High

288710

NPM3
Nucleoplasmin-3

1

10

High-throughput

0.445

High

290645

SURF6
Surfeit locus protein 6

1

6

High-throughput

0.445

High

428872

RLA0
Large ribosomal subunit protein uL10

1

11

High-throughput

0.445

High

485281

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

19

High-throughput

0.445

High

516434

CALM2
Calmodulin-2

1

2

High-throughput

0.445

High

601777

HMGA1
High mobility group protein HMG-I/HMG-Y

1

2

High-throughput

0.445

High

960177

RL26
Large ribosomal subunit protein uL24

1

13

High-throughput

0.445

High

1037280

H11
Histone H1.1

1

13

High-throughput

0.445

High

1336609

PAPD5
Terminal nucleotidyltransferase 4B

1

5

High-throughput

0.445

High

1340176

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

1

High-throughput

0.445

High

1340442

MF14A
Hippocampus abundant transcript 1 protein

1

2

High-throughput

0.445

High

1340451

ZN692
Zinc finger protein 692

1

3

High-throughput

0.445

High

1340466

LYAR
Cell growth-regulating nucleolar protein

1

5

High-throughput

0.445

High

1340474

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

High-throughput

0.445

High

1327090

FBXL6
F-box/LRR-repeat protein 6

1

4

High-throughput

0.437

High

1340457

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.437

High

1340473

XPO7
Exportin-7

1

19

High-throughput

0.437

High

1340488

MAFB
Transcription factor MafB

1

8

High-throughput

0.437

High

134341

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.426

High

839595

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.426

High

1009259

PRR3
Proline-rich protein 3

1

0

High-throughput

0.426

High

1315232

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.426

High

1340446

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.426

High

887040

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.408

High

516558

CALM3
Calmodulin-3

1

2

High-throughput

0.407

High

649374

H1T
Histone H1t

1

13

High-throughput

0.407

High

1248708

SBSN
Suprabasin

1

1

High-throughput

0.407

High

1288431

SO6A1
Solute carrier organic anion transporter family member 6A1

1

1

High-throughput

0.407

High

1012558

RT34
Small ribosomal subunit protein mS34

2

0

High-throughput

0.328

High

1247372

ATRAP
Type-1 angiotensin II receptor-associated protein

1

0

High-throughput

0.299

High

1011322

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.279

Low

1012728

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.279

Low

1340482

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

652656

GNLY
Granulysin

1

0

High-throughput

0.232

Low

1149529

CDSN
Corneodesmosin

1

0

High-throughput

0.232

Low

1252633

ZN574
Zinc finger protein 574

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025