Interactor 1: IFNL1 (Q8IU54)
Interferon lambda-1 (IFN-lambda-1) (Cytokine Zcyto21) (Interleukin-29) (IL-29)
Gene: IFNL1

Interactor 2: INLR1 (Q8IU57)
Interferon lambda receptor 1 (IFN-lambda receptor 1) (IFN-lambda-R1) (Cytokine receptor class-II member 12) (Cytokine receptor family 2 member 12) (CRF2-12) (Interleukin-28 receptor subunit alpha) (IL-28 receptor subunit alpha) (IL-28R-alpha) (IL-28RA) (Likely interleukin or cytokine receptor 2) (LICR2)
Gene: IFNLR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.90 0.614

The method score is based on:

Property Details
Experiments 20934432
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL28A~Tissue_fac
Common GO terms GO:0008285 - negative regulation of cell population proliferation
GO:0032002 - interleukin-28 receptor complex
GO:0038196 - type III interferon-mediated signaling pathway
GO:0051607 - defense response to virus
GO:0098586 - cellular response to virus
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024