HitPredict

Interactor 1: TF2LX (Q8IUE1)
Homeobox protein TGIF2LX (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, X-linked) (TGIF-like on the X)
Gene: TGIF2LX

Interactor 2: SP130 (Q9H0E3)
Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130)
Gene: SAP130

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 1048
+	Hs
		1326059 TGIF2_HUMAN (33-240): 3.01e-42: 145: 40.72		SP130_HUMAN (1-1048): 2.19e-131: 426: 100.00
+	Hs
		1300932 TGIF2_HUMAN (33-240): 3.01e-42: 145: 40.72		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		1300973 LHX3_HUMAN (27-220): 3.24e-37: 136: 16.18		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		1243849 LHX3_HUMAN (27-220): 3.24e-37: 136: 16.18		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83
+	Hs
		1281169 LHX4_HUMAN (27-225): 8.02e-33: 124: 11.48		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		238117 LMX1B_HUMAN (1-236): 1.81e-32: 123: 10.55		CIC_HUMAN (284-939): 3.09e-10: 67: 10.76
+	Hs
		1243832 LHX4_HUMAN (27-225): 8.02e-33: 124: 11.48		KMT2C_HUMAN (364-832): 7.84e-09: 62.5: 15.83