Interactor 1: RIOX2 (Q8IUF8)
Ribosomal oxygenase 2 (60S ribosomal protein L27a histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA) (EC 1.14.11.79) (Histone lysine demethylase MINA) (MYC-induced nuclear antigen) (Mineral dust-induced gene protein) (Nucleolar protein 52) (Ribosomal oxygenase MINA) (ROX)
Gene: RIOX2

Interactor 2: RIOX2 (Q8IUF8)
Ribosomal oxygenase 2 (60S ribosomal protein L27a histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA) (EC 1.14.11.79) (Histone lysine demethylase MINA) (MYC-induced nuclear antigen) (Mineral dust-induced gene protein) (Nucleolar protein 52) (Ribosomal oxygenase MINA) (ROX)
Gene: RIOX2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 25416956, 16189514, 32296183, 24814345, unassigned1304
Identification Methods two hybrid, two hybrid array, x-ray crystallography, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains JmjC_2~JmjC_2, JmjC_2~ROXA-like_wH
Common GO terms GO:0003714 - transcription corepressor activity
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
GO:0005730 - nucleolus
GO:0005829 - cytosol
and 6 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 465
Hs

1 465
+ Hs
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024