HitPredict

Interactor 1: KIBRA (Q8IX03)
Protein KIBRA (HBeAg-binding protein 3) (Kidney and brain protein) (KIBRA) (WW domain-containing protein 1)
Gene: WWC1

Interactor 2: RHPN1 (Q8TCX5)
Rhophilin-1 (GTP-Rho-binding protein 1)
Gene: RHPN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1113 Hs			1 670
+	Hs
		1149652 WWC2_HUMAN (5-1113): 0: 779: 48.44		RHPN1_HUMAN (1-670): 0: 708: 100.00
+	Hs
		1220088 KIBRA_HUMAN (1-1113): 0: 842: 100.00		LIN7C_HUMAN (452-617): 1.43e-35: 135: 21.32
+	Hs
		1220068 KIBRA_HUMAN (1-1113): 0: 842: 100.00		INADL_HUMAN (360-666): 4.51e-11: 68.4: 10.31
+	Hs
		1260380 NED4L_HUMAN (656-807): 2.04e-33: 141: 15.09		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Hs
		1260379 ITCH_HUMAN (2-164): 5.57e-30: 130: 22.94		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Hs
		1260412 WWOX_HUMAN (5-113): 1.68e-31: 130: 29.46		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Mm
		93273 E9PXB7_MOUSE (2-423): 1.73e-84: 294: 16.77		DLG4_MOUSE (460-595): 1.7e-18: 91.9: 19.86
+	Mm
		93267 E9PXB7_MOUSE (2-423): 1.73e-84: 294: 16.77		DLG3_MOUSE (419-592): 3.45e-16: 84.6: 16.85
+	Dm
		1374363 SUDX_DROME (669-770): 6.76e-12: 72.1: 16.35		Q9VUH6_DROME (109-518): 8.21e-68: 244: 22.07
+	Sc
		765321 RSP5_YEAST (673-956): 5.26e-12: 72.5: 11.44		BRO1_YEAST (109-521): 1.02e-66: 236: 19.58
+	Mm
		802298 SYT1_MOUSE (661-794): 6.97e-47: 175: 26.87		DLG4_MOUSE (460-595): 1.7e-18: 91.9: 19.86
+	Mm
		808344 NEDD4_MOUSE (631-1101): 1.65e-38: 157: 12.04		DLG3_MOUSE (419-592): 3.45e-16: 84.6: 16.85
+	Mm
		1143429 NED4L_MOUSE (671-807): 7.62e-32: 136: 13.29		DLG4_MOUSE (460-595): 1.7e-18: 91.9: 19.86
+	Hs
		1271021 NED4L_HUMAN (656-807): 2.04e-33: 141: 15.09		DLG3_HUMAN (438-592): 2.5e-14: 78.8: 17.58
+	Mm
		292484 YAP1_MOUSE (1-56): 2.33e-11: 69.5: 41.67		LIN7C_MOUSE (452-617): 1.43e-35: 135: 21.32
+	Hs
		1246432 WWP1_HUMAN (2-162): 9.09e-26: 117: 25.77		INADL_HUMAN (360-666): 4.51e-11: 68.4: 10.31
+	Mm
		1143518 MAGI3_MOUSE (43-174): 3.6e-11: 69.9: 23.36		DLG4_MOUSE (460-595): 1.7e-18: 91.9: 19.86
+	Hs
		1246425 MAGI1_HUMAN (36-163): 3.73e-13: 76.5: 25.95		INADL_HUMAN (360-666): 4.51e-11: 68.4: 10.31
+	Mm
		809075 YAP1_MOUSE (1-56): 2.33e-11: 69.5: 41.67		INADL_MOUSE (346-635): 9.94e-13: 73.8: 12.84
+	Hs
		125592 WWP2_HUMAN (35-303): 1.01e-10: 68.2: 16.36		INADL_HUMAN (360-666): 4.51e-11: 68.4: 10.31