HitPredict

Interactor 1: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Interactor 2: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 32877691, 26496610, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0007015 - actin filament organization GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 970
+	Hs
		545558 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		894309 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		925516 RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		1070477 RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70		MYO5A_HUMAN (10-937): 0: 1027: 29.21
+	Hs
		725125 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		892610 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		MYO10_HUMAN (1-945): 0: 991: 26.68
+	Hs
		925728 RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Hs
		725138 RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		724776 RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		724757 RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		900798 RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		914486 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		MYO5A_HUMAN (10-937): 0: 1027: 29.21
+	Hs
		894825 RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Hs
		1079976 RB11B_HUMAN (416-572): 8.06e-22: 96.2: 20.37		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Hs
		914453 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Rn
		914521 RB11A_RAT (416-572): 8.23e-22: 96.2: 20.37		MYO5B_RAT (26-964): 0: 998: 28.82
+	Hs
		545699 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		894586 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		925731 RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		916073 RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01