HitPredict

Interactor 1: MIRO1 (Q8IXI2)
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)
Gene: RHOT1

Interactor 2: TRAK1 (Q9UPV9)
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
Gene: TRAK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	33961781, 16630562, 19135897, 24995978
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 953
+	Hs
		1220707 MIRO2_HUMAN (1-618): 0: 764: 59.81		TRAK1_HUMAN (1-953): 0: 646: 100.00
+	Hs
		230512 MIRO1_HUMAN (1-618): 0: 837: 100.00		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Hs
		230511 MIRO2_HUMAN (1-618): 0: 764: 59.81		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Dm
		1213181 MIRO_DROME (2-614): 0: 712: 50.94		MILT_DROME (258-522): 2.53e-09: 63.3: 10.94
+	Hs
		925344 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		MRCKA_HUMAN (4-678): 5.5e-23: 108: 10.13
+	Hs
		1070238 RAB35_HUMAN (5-168): 1.96e-72: 233: 25.90		MRCKA_HUMAN (4-678): 5.5e-23: 108: 10.13
+	Hs
		914124 RB11A_HUMAN (5-201): 1.75e-71: 231: 19.60		MRCKA_HUMAN (4-678): 5.5e-23: 108: 10.13
+	Hs
		925356 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		MRCKG_HUMAN (23-365): 5.69e-20: 98.5: 15.43
+	Hs
		148636 RAB1A_HUMAN (5-190): 5.36e-74: 237: 20.21		CTRO_HUMAN (33-527): 4.9e-19: 95.4: 11.83
+	Hs
		148653 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		CTRO_HUMAN (33-527): 4.9e-19: 95.4: 11.83
+	Mm
		823530 RAC1_MOUSE (3-181): 7.62e-73: 234: 23.83		CTRO_MOUSE (31-512): 1.05e-18: 94.3: 10.72
+	Hs
		914190 RB11A_HUMAN (5-201): 1.75e-71: 231: 19.60		RFIP4_HUMAN (110-403): 7.2e-20: 97: 19.28
+	Hs
		1070477 RAB35_HUMAN (5-168): 1.96e-72: 233: 25.90		MYO5A_HUMAN (47-567): 2.47e-18: 93.1: 11.22
+	Hs
		914486 RB11A_HUMAN (5-201): 1.75e-71: 231: 19.60		MYO5A_HUMAN (47-567): 2.47e-18: 93.1: 11.22
+	Hs
		724757 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		MYH9_HUMAN (195-661): 7.37e-17: 88.3: 10.53
+	Hs
		254468 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		ROCK2_HUMAN (155-590): 1.63e-16: 87: 11.53
+	Hs
		254466 RB11A_HUMAN (5-201): 1.75e-71: 231: 19.60		ROCK2_HUMAN (155-590): 1.63e-16: 87: 11.53
+	Hs
		925766 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		MRCKB_HUMAN (14-364): 3.56e-15: 82.6: 10.71
+	Hs
		1070480 RAB35_HUMAN (5-168): 1.96e-72: 233: 25.90		MRCKB_HUMAN (14-364): 3.56e-15: 82.6: 10.71
+	Hs
		256700 RB11A_HUMAN (5-201): 1.75e-71: 231: 19.60		RFIP3_HUMAN (292-577): 4.62e-09: 62.3: 15.07