HitPredict

Interactor 1: PHC2 (Q8IXK0)
Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2)
Gene: PHC2

Interactor 2: R4GMX3 (R4GMX3)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4)
Gene: COMMD3-BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	25910212
Identification Methods	two hybrid bait and prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Hs			1 469
+	Hs
		717999 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		BMI1_HUMAN (144-469): 2.11e-149: 430: 100.00
+	Mm
		639480 PHC2_MOUSE (1-858): 2.51e-83: 287: 85.40		BMI1_MOUSE (144-469): 3.13e-146: 422: 96.93
+	Hs
		718408 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		PCGF2_HUMAN (144-463): 1.09e-115: 345: 61.36
+	Mm
		620794 PHC2_MOUSE (1-858): 2.51e-83: 287: 85.40		PCGF2_MOUSE (144-463): 4.85e-112: 336: 61.06
+	Hs
		717684 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		BMI1_HUMAN (144-469): 2.11e-149: 430: 100.00
+	Hs
		1108515 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		PCGF3_HUMAN (147-371): 3.08e-67: 217: 34.73
+	Hs
		1220881 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		PCGF1_HUMAN (119-372): 4.08e-62: 204: 33.71
+	Hs
		1220877 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		RING2_HUMAN (113-375): 2.16e-59: 200: 15.39
+	Hs
		1220886 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		PCGF6_HUMAN (141-378): 2.91e-59: 200: 34.55
+	Hs
		718390 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		PCGF2_HUMAN (144-463): 1.09e-115: 345: 61.36
+	Hs
		1197568 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		PCGF5_HUMAN (144-371): 5.82e-54: 183: 30.44
+	Mm
		1321743 PHC2_MOUSE (1-858): 2.51e-83: 287: 85.40		RING2_MOUSE (113-375): 1.71e-59: 200: 15.39
+	Hs
		987988 PHC2_HUMAN (1-858): 9.36e-98: 326: 100.00		RING1_HUMAN (123-258): 6.48e-36: 139: 21.17
+	Mm
		193416 PHC2_MOUSE (1-858): 2.51e-83: 287: 85.40		RING1_MOUSE (123-258): 3.02e-36: 140: 21.17
+	Hs
		943064 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		PCGF3_HUMAN (147-371): 3.08e-67: 217: 34.73
+	Hs
		943087 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		PCGF1_HUMAN (119-372): 4.08e-62: 204: 33.71
+	Hs
		943084 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		RING2_HUMAN (113-375): 2.16e-59: 200: 15.39
+	Hs
		943070 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		PCGF5_HUMAN (144-371): 5.82e-54: 183: 30.44
+	Hs
		943066 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		Q5T8Z6_HUMAN (144-248): 3.82e-47: 160: 100.00
+	Hs
		943060 PHC1_HUMAN (44-858): 3.94e-44: 174: 26.40		RING1_HUMAN (123-258): 6.48e-36: 139: 21.17