HitPredict

Interactor 1: PSD12 (O00232)
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
Gene: PSMD12

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	14743216, 17353931
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 456 Hs			1 522
+	Hs
		121882 PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		122065 PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Mm
		1113362 Q3UWW9_MOUSE (27-443): 1.58e-90: 283: 15.67		RO52_MOUSE (51-403): 1.44e-45: 167: 14.17