Interactor 1: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Interactor 2: NSE2 (Q96MF7)
E3 SUMO-protein ligase NSE2 (EC 2.3.2.-) (E3 SUMO-protein transferase NSE2) (MMS21 homolog) (hMMS21) (Non-structural maintenance of chromosomes element 2 homolog) (Non-SMC element 2 homolog)
Gene: NSMCE2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.625

The method score is based on:

Property Details
Experiments 32389690, 16055714
Identification Methods biochemical, two hybrid, affinity chromatography technology
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 8 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1101
Hs

1 247
+ Hs
+ At
+ Sp
+ Dm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024