HitPredict

Interactor 1: MILK2 (Q8IY33)
MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2)
Gene: MICALL2

Interactor 2: RAB8B (Q92930)
Ras-related protein Rab-8B
Gene: RAB8B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0005886 - plasma membrane GO:0032456 - endocytic recycling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 904 Hs			1 207
+	Hs
		894763 MILK2_HUMAN (1-904): 9.07e-111: 363: 100.00		RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61
+	Hs
		845867 MILK2_HUMAN (1-904): 9.07e-111: 363: 100.00		RAB13_HUMAN (1-206): 1.1e-88: 260: 64.08
+	Hs
		894773 EHBP1_HUMAN (3-890): 4.36e-79: 281: 16.01		RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61
+	Hs
		914223 EHBP1_HUMAN (3-890): 4.36e-79: 281: 16.01		RB11A_HUMAN (4-205): 8.61e-88: 259: 43.27
+	Mm
		292526 ACTN3_MOUSE (2-219): 6.55e-70: 251: 30.28		RAB10_MOUSE (1-197): 7.97e-95: 276: 70.20
+	Hs
		895513 MILK1_HUMAN (2-885): 2.52e-61: 225: 29.81		RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20
+	Hs
		1232324 MILK1_HUMAN (2-885): 2.52e-61: 225: 29.81		RAB8B_HUMAN (1-207): 4.25e-93: 272: 100.00
+	Hs
		894767 MILK1_HUMAN (2-885): 2.52e-61: 225: 29.81		RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61
+	Hs
		914014 SPTB2_HUMAN (2-219): 3.33e-61: 229: 30.28		RB11A_HUMAN (4-205): 8.61e-88: 259: 43.27
+	Mm
		1112011 MILK2_MOUSE (1-888): 7.2e-61: 226: 40.66		RAB13_MOUSE (1-202): 9.22e-89: 261: 64.85
+	Hs
		895525 MICA1_HUMAN (372-865): 2.36e-55: 210: 18.15		RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20
+	Hs
		845869 MILK1_HUMAN (2-885): 2.52e-61: 225: 29.81		RAB13_HUMAN (1-206): 1.1e-88: 260: 64.08
+	Hs
		914208 MILK1_HUMAN (2-885): 2.52e-61: 225: 29.81		RB11A_HUMAN (4-205): 8.61e-88: 259: 43.27
+	Hs
		918915 MICA1_HUMAN (372-865): 2.36e-55: 210: 18.15		RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94
+	Hs
		1255762 MICA1_HUMAN (372-865): 2.36e-55: 210: 18.15		RAB1B_HUMAN (1-204): 3.94e-92: 269: 51.96
+	Hs
		894779 MICA1_HUMAN (372-865): 2.36e-55: 210: 18.15		RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61
+	Hs
		895507 MICA3_HUMAN (120-749): 1.02e-11: 71.5: 9.15		RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20
+	Hs
		1186079 MICA3_HUMAN (120-749): 1.02e-11: 71.5: 9.15		RAB8B_HUMAN (1-207): 4.25e-93: 272: 100.00
+	Hs
		894754 MICA3_HUMAN (120-749): 1.02e-11: 71.5: 9.15		RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61
+	Hs
		914166 MICA3_HUMAN (120-749): 1.02e-11: 71.5: 9.15		RB11A_HUMAN (4-205): 8.61e-88: 259: 43.27