HitPredict

Interactor 1: SPB1 (Q8IY81)
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)
Gene: FTSJ3

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21182203
Identification Methods	cosedimentation through density gradient, affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 847 Hs			1 530
+	Hs
		369967 SPB1_HUMAN (1-834): 0: 645: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269725 MDN1_HUMAN (327-776): 7.1e-58: 218: 11.07		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1268061 MY18A_HUMAN (277-841): 5.38e-46: 181: 11.04		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370528 MDN1_HUMAN (327-776): 7.1e-58: 218: 11.07		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1068618 PLEC_HUMAN (273-847): 4.47e-36: 150: 13.04		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370120 MY18A_HUMAN (277-841): 5.38e-46: 181: 11.04		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369641 PLEC_HUMAN (273-847): 4.47e-36: 150: 13.04		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377727 MDN1_HUMAN (327-776): 7.1e-58: 218: 11.07		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		1154059 NIPBL_HUMAN (281-842): 1.3e-11: 71.1: 11.19		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1270066 PCLO_HUMAN (412-838): 7.31e-09: 61.9: 10.78		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369815 NIPBL_HUMAN (281-842): 1.3e-11: 71.1: 11.19		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		782571 NIPBL_HUMAN (281-842): 1.3e-11: 71.1: 11.19		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377401 NIPBL_HUMAN (281-842): 1.3e-11: 71.1: 11.19		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487792 MDN1_HUMAN (327-776): 7.1e-58: 218: 11.07		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487627 MY18A_HUMAN (277-841): 5.38e-46: 181: 11.04		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487522 NIPBL_HUMAN (281-842): 1.3e-11: 71.1: 11.19		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59