HitPredict

Interactor 1: SPB1 (Q8IY81)
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)
Gene: FTSJ3

Interactor 2: WDR55 (Q9H6Y2)
WD repeat-containing protein 55
Gene: WDR55

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FtsJ~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 847 Hs			1 383
+	Hs
		1222359 SPB1_HUMAN (1-834): 0: 645: 100.00		SNR40_HUMAN (286-380): 2.41e-11: 66.3: 20.00
+	Sc
		630845 SPB1_YEAST (1-846): 9.02e-133: 418: 33.99		NLE1_YEAST (110-378): 5.53e-63: 211: 13.13
+	Hs
		1345855 MDN1_HUMAN (327-776): 7.1e-58: 218: 11.07		NLE1_HUMAN (110-378): 3e-64: 214: 12.58
+	Hs
		1268063 MY18A_HUMAN (277-841): 5.38e-46: 181: 11.04		FBXW7_HUMAN (3-275): 8.88e-66: 223: 15.25
+	Hs
		1202785 TRM7_HUMAN (5-225): 3.08e-100: 316: 39.30		WDR5B_HUMAN (282-378): 6.05e-14: 74: 19.59
+	Hs
		1068625 PLEC_HUMAN (273-847): 4.47e-36: 150: 13.04		FBXW7_HUMAN (3-275): 8.88e-66: 223: 15.25
+	Sc
		767636 MDN1_YEAST (432-846): 7.45e-12: 71.9: 9.65		GLE2_YEAST (13-327): 1.19e-66: 217: 22.46
+	Sc
		630897 MDN1_YEAST (432-846): 7.45e-12: 71.9: 9.65		NLE1_YEAST (110-378): 5.53e-63: 211: 13.13
+	Sp
		252177 MDN1_SCHPO (478-844): 3.15e-09: 63: 10.90		NLE1_SCHPO (125-378): 3.81e-62: 209: 15.33
+	Hs
		903399 MY18A_HUMAN (277-841): 5.38e-46: 181: 11.04		WDR5_HUMAN (282-378): 5.94e-15: 77: 19.59
+	Hs
		903240 PLEC_HUMAN (273-847): 4.47e-36: 150: 13.04		WDR5_HUMAN (282-378): 5.94e-15: 77: 19.59