Protein: RFC3
Replication factor C subunit 3 (Replication factor C3) (Activator 1 40 kDa subunit)

Gene: RFC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 111
UniProt ID: P38629

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751269

RFC2
Replication factor C subunit 2

12

15

Small-scale

0.980

High

751278

CTF18
Chromosome transmission fidelity protein 18

7

18

Small-scale

0.962

High

751267

RFC4
Replication factor C subunit 4

5

15

Small-scale

0.931

High

747100

RFC5
Replication factor C subunit 5

5

16

High-throughput

0.927

High

550541

PCNA
Proliferating cell nuclear antigen

4

16

Small-scale

0.896

High

751260

RFC1
Replication factor C subunit 1

3

18

High-throughput

0.855

High

751303

RUVB2
RuvB-like protein 2

2

11

High-throughput

0.767

High

697289

RAD24
Checkpoint protein RAD24

8

20

Small-scale

0.752

High

751297

ELG1
Telomere length regulation protein ELG1

6

18

Small-scale

0.729

High

703791

PRS6B
26S proteasome regulatory subunit 6B homolog

1

7

High-throughput

0.691

High

392414

H2A2
Histone H2A.2

3

7

High-throughput

0.650

High

744517

DPOA2
DNA polymerase alpha subunit B

2

2

High-throughput

0.621

High

751262

CTF8
Chromosome transmission fidelity protein 8

2

3

Small-scale

0.621

High

680668

HS104
Heat shock protein 104

1

2

High-throughput

0.618

High

751268

ATAD2
ATPase histone chaperone YTA7

1

8

High-throughput

0.618

High

751287

RUVB1
RuvB-like protein 1

1

11

High-throughput

0.618

High

751302

SMT3
Ubiquitin-like protein SMT3

2

4

Small-scale

0.586

High

356449

H4
Histone H4

2

7

High-throughput

0.584

High

366222

HSP82
ATP-dependent molecular chaperone HSP82

2

6

High-throughput

0.584

High

558037

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

3

High-throughput

0.584

High

630407

RNQ1
[PIN+] prion protein RNQ1

1

1

High-throughput

0.536

High

676014

XPO1
Exportin-1

1

9

High-throughput

0.536

High

751273

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

6

High-throughput

0.536

High

751284

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

7

High-throughput

0.536

High

751274

ECO1
N-acetyltransferase ECO1

1

3

Small-scale

0.515

High

745540

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

751289

YM71
NADP-dependent 3-hydroxy acid dehydrogenase

1

0

High-throughput

0.513

High

745634

NU170
Nucleoporin NUP170

1

3

High-throughput

0.504

High

342010

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.500

High

423843

ATPA
ATP synthase subunit alpha, mitochondrial

1

7

High-throughput

0.500

High

424493

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.500

High

454306

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.500

High

520972

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.500

High

554636

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

556021

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.500

High

562373

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.500

High

693293

RPN2
26S proteasome regulatory subunit RPN2

1

4

High-throughput

0.500

High

751276

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.500

High

751304

CMR1
DNA damage-binding protein CMR1

1

7

High-throughput

0.481

High

343594

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.479

High

381703

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.479

High

751293

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.479

High

141299

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

355470

H2B1
Histone H2B.1

1

14

High-throughput

0.479

High

355882

H2B2
Histone H2B.2

1

14

High-throughput

0.479

High

358038

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.479

High

383114

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.479

High

389640

DNLI1
DNA ligase 1

1

3

Small-scale

0.479

High

404565

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.479

High

405593

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.479

High

407017

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

407885

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

413479

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

425922

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.479

High

457025

SWI6
Regulatory protein SWI6

1

3

High-throughput

0.479

High

471026

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.479

High

472163

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.479

High

480074

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.479

High

480642

RS8A
Small ribosomal subunit protein eS8A

1

5

High-throughput

0.479

High

482236

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

543665

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

602339

DPOE
DNA polymerase epsilon catalytic subunit A

1

1

High-throughput

0.479

High

627997

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

631847

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

634048

DCC1
Sister chromatid cohesion protein DCC1

1

7

High-throughput

0.479

High

645413

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

662110

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

688218

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

689873

ASF1
Histone chaperone ASF1

1

3

Small-scale

0.479

High

698785

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

3

High-throughput

0.479

High

700378

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.479

High

706244

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

730788

CENPA
Histone H3-like centromeric protein CSE4

1

14

High-throughput

0.479

High

742765

GBLP
Small ribosomal subunit protein RACK1

1

10

High-throughput

0.479

High

751261

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

751264

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.479

High

751270

ULP2
Ubiquitin-like-specific protease 2

1

3

High-throughput

0.479

High

751271

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.479

High

751277

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.479

High

751280

RL26B
Large ribosomal subunit protein uL24B

1

6

High-throughput

0.479

High

751282

H3
Histone H3

1

14

High-throughput

0.479

High

751283

CTF4
DNA polymerase alpha-binding protein

1

8

Small-scale

0.479

High

751285

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

751288

SIZ1
E3 SUMO-protein ligase SIZ1

1

2

High-throughput

0.479

High

751290

HRQ1
ATP-dependent helicase HRQ1

1

8

Small-scale

0.479

High

751291

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.479

High

751294

SGO1
Shugoshin

1

3

High-throughput

0.479

High

751295

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.479

High

751298

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

751299

SCC1
Sister chromatid cohesion protein 1

1

4

High-throughput

0.479

High

751301

SIZ2
E3 SUMO-protein ligase SIZ2

1

2

High-throughput

0.479

High

534969

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

751279

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

751296

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

751300

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.458

High

360863

TBB
Tubulin beta chain

1

1

High-throughput

0.457

High

751275

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

3

High-throughput

0.457

High

450031

HSP73
Heat shock protein SSA3

1

6

High-throughput

0.445

High

511159

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

633193

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

751265

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

751266

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

751281

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.445

High

751286

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

701411

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

751292

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

540224

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

0

High-throughput

0.279

Low

634270

YCE2
Putative uncharacterized protein YCL042W

1

0

High-throughput

0.279

Low

741177

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.279

Low

751272

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

751263

MNN9
Mannan polymerase complexes subunit MNN9

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024