HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: CHAP1 (Q96JM3)
Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828)
Gene: CHAMP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37071664, 37059091
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1834 Hs			1 812
+	Hs
		231248 SLX4_HUMAN (1-1834): 0: 1486: 100.00		ZEB2_HUMAN (412-792): 8.3e-41: 164: 12.76
+	Hs
		1056885 SLX4_HUMAN (1-1834): 0: 1486: 100.00		MDC1_HUMAN (135-725): 6.26e-13: 74.9: 9.98
+	Hs
		1222496 SLX4_HUMAN (1-1834): 0: 1486: 100.00		CBP_HUMAN (165-566): 3.23e-11: 69.6: 17.59
+	Hs
		801310 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		CHAP1_HUMAN (1-812): 1.59e-115: 371: 100.00
+	Hs
		1056937 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		CHAP1_HUMAN (1-812): 1.59e-115: 371: 100.00
+	Hs
		741073 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		ZEB1_HUMAN (361-798): 4.28e-41: 165: 16.25
+	Hs
		554259 MUC1_HUMAN (1127-1735): 4.53e-16: 87: 11.22		MUC1_HUMAN (64-692): 4.58e-33: 140: 12.34
+	Hs
		801096 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		IF4G1_HUMAN (112-705): 1.45e-24: 112: 11.69
+	Dm
		113976 M9PB30_DROME (1116-1784): 2.28e-27: 124: 8.45		M9PB30_DROME (364-737): 2.93e-09: 63.4: 8.29
+	Hs
		801143 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		MDC1_HUMAN (135-725): 6.26e-13: 74.9: 9.98
+	Hs
		152608 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		KMT2D_HUMAN (104-630): 1.61e-09: 64.2: 19.02
+	Hs
		965118 ANK2_HUMAN (1147-1751): 8.46e-11: 69.7: 10.18		OBSCN_HUMAN (136-679): 3.63e-21: 102: 15.54
+	Mm
		1351630 PCLO_MOUSE (826-1830): 1.25e-15: 85.9: 8.22		PCLO_MOUSE (55-730): 8.91e-10: 64.9: 11.11
+	Hs
		1056827 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		MDC1_HUMAN (135-725): 6.26e-13: 74.9: 9.98
+	Hs
		1056910 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		CBP_HUMAN (165-566): 3.23e-11: 69.6: 17.59
+	Hs
		1056876 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		MICA3_HUMAN (182-723): 2.31e-10: 66.9: 11.44
+	Hs
		1270755 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		CBP_HUMAN (165-566): 3.23e-11: 69.6: 17.59
+	Hs
		152675 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		KMT2D_HUMAN (104-630): 1.61e-09: 64.2: 19.02
+	Hs
		1170076 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		SRCAP_HUMAN (140-725): 3.61e-09: 63: 9.53