Protein: SAP
Prosaposin (Sulfated glycoprotein 1) (SGP-1) [Cleaved into: Saposin-A; Saposin-B-Val; Saposin-B; Saposin-C; Saposin-D]

Gene: SAP, Psap
Organism: Mus musculus
Interactions: 93
UniProt ID: Q61207

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0001865 - NK T cell differentiation
GO:0002020 - protease binding
GO:0003335 - corneocyte development
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1222517

Q9D2V3
Progranulin

1

2

High-throughput

0.561

High

73025

B1ASP2
Tyrosine-protein kinase

1

1

High-throughput

0.479

High

147655

THOC4
THO complex subunit 4

1

1

High-throughput

0.479

High

398461

CFAD
Complement factor D

1

1

High-throughput

0.479

High

528399

CATB
Cathepsin B

1

2

High-throughput

0.479

High

559573

GELS
Gelsolin

1

1

High-throughput

0.479

High

602289

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.479

High

613659

CATD
Cathepsin D

1

2

High-throughput

0.479

High

619188

THRB
Prothrombin

1

1

High-throughput

0.479

High

638273

CYTC
Cystatin-C

1

1

High-throughput

0.479

High

705243

GRN
Progranulin

1

2

High-throughput

0.479

High

801624

HSPA9
Stress-70 protein, mitochondrial

1

4

High-throughput

0.479

High

858746

MYO1B
Unconventional myosin-Ib

1

2

High-throughput

0.479

High

932544

DDX6
Probable ATP-dependent RNA helicase DDX6

1

1

High-throughput

0.479

High

943005

FUS
RNA-binding protein FUS

1

1

High-throughput

0.479

High

976068

KCAB2
Voltage-gated potassium channel subunit beta-2

1

1

High-throughput

0.479

High

1058801

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.479

High

1191002

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

1

High-throughput

0.479

High

1222474

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

1222476

DDX3X
ATP-dependent RNA helicase DDX3X

1

1

High-throughput

0.479

High

1222481

SORT
Sortilin

1

1

Small-scale

0.479

High

1222482

GGYF2
GRB10-interacting GYF protein 2

1

1

High-throughput

0.479

High

1222487

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

1222491

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

1

High-throughput

0.479

High

1222493

BCLF1
Bcl-2-associated transcription factor 1

1

1

High-throughput

0.479

High

1222500

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

High-throughput

0.479

High

1222502

DDX1
ATP-dependent RNA helicase DDX1

1

2

High-throughput

0.479

High

1222513

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.479

High

1222522

ALRF2
Aly/REF export factor 2

1

1

High-throughput

0.479

High

1222523

MYO1C
Unconventional myosin-Ic

1

1

High-throughput

0.479

High

313381

RBM3
RNA-binding protein 3

1

0

High-throughput

0.458

High

570333

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.458

High

576860

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

628498

VIME
Vimentin

1

0

High-throughput

0.458

High

666140

MPRD
Cation-dependent mannose-6-phosphate receptor

1

0

High-throughput

0.458

High

868411

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

868956

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.458

High

908575

ADT2
ADP/ATP translocase 2

1

0

High-throughput

0.458

High

958398

ARP2
Actin-related protein 2

1

0

High-throughput

0.458

High

967626

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

982053

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.458

High

985406

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

986922

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

997245

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.458

High

1021207

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

1021470

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

1023495

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.458

High

1189988

Q3UCL2
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

1221442

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

1222478

CYTB
Cystatin-B

1

0

High-throughput

0.458

High

1222479

IFIT1
Antiviral innate immune response effector IFIT1

1

0

High-throughput

0.458

High

1222480

SRSF1
Serine/arginine-rich splicing factor 1

1

0

High-throughput

0.458

High

1222483

FA98B
Protein FAM98B

1

0

High-throughput

0.458

High

1222484

ACTBL
Beta-actin-like protein 2

1

0

High-throughput

0.458

High

1222488

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.458

High

1222490

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

0

High-throughput

0.458

High

1222492

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.458

High

1222495

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.458

High

1222496

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.458

High

1222497

MYH9
Myosin-9

1

0

High-throughput

0.458

High

1222501

STK38
Serine/threonine-protein kinase 38

1

0

High-throughput

0.458

High

1222504

PTGR1
Prostaglandin reductase 1

1

0

High-throughput

0.458

High

1222505

TBB6
Tubulin beta-6 chain

1

0

High-throughput

0.458

High

1222506

MEP50
Methylosome protein WDR77

1

0

High-throughput

0.458

High

1222507

ARP3
Actin-related protein 3

1

0

High-throughput

0.458

High

1222509

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.458

High

1222510

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.458

High

1222512

RTRAF
RNA transcription, translation and transport factor protein

1

0

High-throughput

0.458

High

1222514

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1222515

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

1222518

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

1222519

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

1222524

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

0

High-throughput

0.458

High

553456

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

0

High-throughput

0.438

High

73942

OTUD4
OTU domain-containing protein 4

1

1

High-throughput

0.437

High

205523

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

1

High-throughput

0.437

High

1201205

TR150
Thyroid hormone receptor-associated protein 3

1

2

High-throughput

0.437

High

1222475

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

1

High-throughput

0.437

High

1222485

IF4B
Eukaryotic translation initiation factor 4B

1

1

High-throughput

0.437

High

1222499

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.437

High

1222503

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

1

High-throughput

0.437

High

1222508

NONO
Non-POU domain-containing octamer-binding protein

1

1

High-throughput

0.437

High

1222521

FLII
Protein flightless-1 homolog

1

1

High-throughput

0.437

High

98323

E9QKZ2
Importin 9

1

0

High-throughput

0.249

Low

480973

NUCL
Nucleolin

1

0

High-throughput

0.249

Low

1222477

SEM4A
Semaphorin-4A

1

0

Small-scale

0.249

Low

1222486

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.249

Low

1222489

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.249

Low

1222494

PDXK
Pyridoxal kinase

1

0

High-throughput

0.249

Low

1222498

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

1222511

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1222516

MCES
mRNA cap guanine-N(7) methyltransferase

1

0

High-throughput

0.249

Low

1222520

TMOD3
Tropomodulin-3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025