HitPredict

Interactor 1: RN103 (O00237)
E3 ubiquitin-protein ligase RNF103 (EC 2.3.2.27) (KF-1) (hKF-1) (RING finger protein 103) (RING-type E3 ubiquitin transferase RNF103) (Zinc finger protein 103 homolog) (Zfp-103)
Gene: RNF103

Interactor 2: UB2E1 (P51965)
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcH6) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)
Gene: UBE2E1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	18615712
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 193
+	Hs
		122270 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2E2_HUMAN (4-193): 2.5e-84: 249: 81.96
+	Hs
		122275 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D4_HUMAN (47-192): 2.38e-81: 239: 63.01
+	Hs
		122263 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		122256 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		122259 RN103_HUMAN (1-685): 0: 1271: 100.00		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		122260 RN103_HUMAN (1-685): 0: 1271: 100.00		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95
+	Hs
		196372 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D4_HUMAN (47-192): 2.38e-81: 239: 63.01
+	Hs
		196294 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		196282 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		196289 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		919792 PJA1_HUMAN (522-669): 3.07e-31: 131: 22.50		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		1245284 PJA1_HUMAN (522-669): 3.07e-31: 131: 22.50		UB2E3_HUMAN (3-193): 1.26e-78: 235: 77.49
+	Hs
		895852 PJA1_HUMAN (522-669): 3.07e-31: 131: 22.50		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		196290 PJA2_HUMAN (526-685): 7.54e-34: 140: 21.71		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95
+	Hs
		851839 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2E1_HUMAN (19-193): 2.75e-82: 244: 100.00
+	Hs
		919775 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2D2_HUMAN (47-192): 8.03e-81: 238: 64.38
+	Hs
		849362 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2D1_HUMAN (47-192): 3.02e-80: 237: 61.64
+	Hs
		1205108 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2E3_HUMAN (3-193): 1.26e-78: 235: 77.49
+	Hs
		895840 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UB2D3_HUMAN (47-192): 2.56e-79: 234: 63.70
+	Hs
		896485 DZIP3_HUMAN (469-680): 8.22e-27: 119: 20.09		UBE2N_HUMAN (45-192): 8.9e-75: 223: 45.95