Interactor 1: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1
Interactor 2: TIFA (Q793I8)
TRAF-interacting protein with FHA domain-containing protein A (TRAF2-binding protein)
Gene: TIFA
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.690 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12566447 |
| Identification Methods | anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FHA~Pkinase |
| Common GO terms | GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045087 - innate immune response |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
