HitPredict

Interactor 1: CDK20 (Q8IZL9)
Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)
Gene: CDK20

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0051301 - cell division
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 496
+	Dm
		618423 CDK1_DROME (1-292): 1.42e-129: 374: 39.80		Q9W4H9_DROME (4-496): 4.54e-116: 351: 68.15
+	Sc
		339758 CDK1_YEAST (3-291): 1.14e-124: 361: 42.71		CDH1_YEAST (44-496): 7.57e-103: 320: 37.81
+	Hs
		625543 CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		415016 CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		625202 CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Hs
		414806 CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Sc
		339740 CDK1_YEAST (3-291): 1.14e-124: 361: 42.71		AMA1_YEAST (144-474): 4.63e-42: 160: 33.25
+	Hs
		625637 CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		415103 CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		960344 CDK5_HUMAN (1-294): 2.23e-128: 370: 45.09		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	At
		621673 CDKA1_ARATH (1-292): 1.49e-129: 373: 42.71		FZR2_ARATH (319-495): 7.11e-20: 94.2: 22.22
+	At
		621679 CDKA1_ARATH (1-292): 1.49e-129: 373: 42.71		FZR3_ARATH (315-495): 1.15e-19: 93.5: 18.48
+	Hs
		625397 CDK2_HUMAN (1-296): 5.66e-140: 400: 43.10		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	At
		621683 CDKA1_ARATH (1-292): 1.49e-129: 373: 42.71		FZR1_ARATH (319-495): 8.99e-18: 87.7: 21.67
+	Hs
		414894 CDK1_HUMAN (1-292): 1.16e-131: 379: 42.18		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Sc
		339473 CDK1_YEAST (3-291): 1.14e-124: 361: 42.71		CDC20_YEAST (319-488): 5.34e-14: 76.2: 18.50
+	Hs
		841208 CDK7_HUMAN (3-304): 2.01e-127: 370: 42.62		TAF5_HUMAN (232-494): 4.48e-09: 60.8: 23.02