HitPredict

Interactor 1: FZR2 (Q8L3Z8)
Protein FIZZY-RELATED 2 (Cell cycle switch protein CCS52A1)
Gene: FZR2

Interactor 2: CD27B (Q8LGU6)
Cell division cycle protein 27 homolog B (CDC27 homolog B) (Protein HOBBIT)
Gene: CDC27B

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	20706207, 17944809
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TPR_16~WD40
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0016567 - protein ubiquitination GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 483 At			1 744
+	At
		1228163 FZR1_ARATH (1-483): 1.51e-98: 306: 78.40		CD27B_ARATH (1-744): 2.51e-130: 406: 100.00
+	At
		1108082 CD205_ARATH (31-464): 9.32e-96: 298: 38.83		CD27B_ARATH (1-744): 2.51e-130: 406: 100.00
+	At
		1228161 FZR3_ARATH (12-483): 1.22e-93: 293: 59.18		CD27B_ARATH (1-744): 2.51e-130: 406: 100.00
+	Sc
		743220 CDH1_YEAST (10-483): 1.24e-100: 314: 36.88		CDC27_YEAST (5-738): 5.8e-84: 284: 23.69
+	Xl
		1150243 Q8AVG7_XENLA (22-467): 9.54e-95: 297: 39.00		Q6DFI7_XENLA (433-718): 4.52e-81: 272: 21.81
+	Hs
		1017371 CDC20_HUMAN (10-461): 5.96e-98: 305: 37.93		CDC16_HUMAN (433-718): 6.71e-77: 261: 20.81
+	Sc
		454922 CDH1_YEAST (10-483): 1.24e-100: 314: 36.88		CDC16_YEAST (425-732): 2.1e-39: 158: 19.38
+	Sp
		140409 SRW1_SCHPO (40-483): 6.51e-92: 291: 41.30		CUT9_SCHPO (433-719): 1.99e-38: 154: 14.63
+	Hs
		1017458 CDC20_HUMAN (10-461): 5.96e-98: 305: 37.93		CDC23_HUMAN (387-741): 5.46e-27: 118: 12.64
+	At
		71746 FZR1_ARATH (1-483): 1.51e-98: 306: 78.40		CDC16_ARATH (414-670): 9.87e-24: 108: 13.36
+	At
		1258614 FZR1_ARATH (1-483): 1.51e-98: 306: 78.40		CDC23_ARATH (274-743): 4.67e-22: 103: 10.64
+	Xl
		1186367 Q8AVG7_XENLA (22-467): 9.54e-95: 297: 39.00		Q7T0N9_XENLA (410-743): 1.65e-23: 107: 11.05
+	At
		71744 FZR3_ARATH (12-483): 1.22e-93: 293: 59.18		CDC16_ARATH (414-670): 9.87e-24: 108: 13.36
+	At
		1228254 FZR3_ARATH (12-483): 1.22e-93: 293: 59.18		CDC23_ARATH (274-743): 4.67e-22: 103: 10.64
+	Hs
		672820 CDC20_HUMAN (10-461): 5.96e-98: 305: 37.93		CDC27_HUMAN (12-307): 4.03e-17: 88: 10.20
+	Hs
		1017459 CDC20_HUMAN (10-461): 5.96e-98: 305: 37.93		APC7_HUMAN (447-731): 7.77e-17: 86.5: 12.21
+	Xl
		1150235 Q6DFD4_XENLA (15-467): 1.42e-96: 302: 38.20		Q6GQ04_XENLA (543-742): 1.64e-14: 79.6: 14.01
+	Sc
		561125 CDH1_YEAST (10-483): 1.24e-100: 314: 36.88		CDC23_YEAST (12-230): 8.51e-10: 64.2: 8.77
+	Xl
		1151587 Q8AVG7_XENLA (22-467): 9.54e-95: 297: 39.00		Q6GQ04_XENLA (543-742): 1.64e-14: 79.6: 14.01
+	Hs
		672926 FZR1_HUMAN (94-483): 2.92e-90: 285: 59.95		CDC27_HUMAN (12-307): 4.03e-17: 88: 10.20