HitPredict

Interactor 1: Q8MRE6 (Q8MRE6)
Defective proboscis extension response 11, isoform B (Defective proboscis extension response 11, isoform C) (GH22307p)
Gene: dpr11

Interactor 2: Q9VDD5 (Q9VDD5)
Common Dpr-interacting protein (GH17632p)
Gene: cDIP

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.694

Property	Details
Experiments	23827685, 26687361
Identification Methods	affinity chromatography technology, solid phase assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	I-set~LRR_8, Ig_3~LRR_8
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 360 Dm			1 554
+	Dm
		1363625 Q9VT83_DROME (76-347): 1.66e-66: 217: 31.35		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		1123768 Q59DX6_DROME (112-343): 6.9e-64: 207: 40.34		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		55648 A1ZB15_DROME (14-359): 3.7e-51: 177: 29.53		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		1363619 Q9VFD9_DROME (54-358): 2.56e-49: 176: 38.25		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		1363620 Q9VKX8_DROME (105-333): 1.55e-48: 169: 25.44		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		65444 A8DZ27_DROME (101-353): 9.38e-49: 168: 33.46		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		51390 A1Z6H9_DROME (103-358): 4.05e-48: 167: 32.09		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		1363622 Q9VMN6_DROME (21-347): 1e-38: 147: 16.06		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		1363623 Q9VMN9_DROME (22-329): 9.91e-38: 142: 14.29		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Dm
		1363629 X2JCW3_DROME (12-315): 6.8e-36: 138: 16.18		Q9VDD5_DROME (1-554): 1.15e-98: 311: 100.00
+	Hs
		259500 LRIG3_HUMAN (6-360): 1.62e-51: 186: 14.60		LRRN2_HUMAN (302-527): 1.21e-19: 94.8: 20.00
+	Hs
		259492 FGFR1_HUMAN (10-356): 1.78e-51: 185: 16.14		LRRN2_HUMAN (302-527): 1.21e-19: 94.8: 20.00
+	Hs
		299578 LRIG2_HUMAN (7-327): 6.22e-53: 190: 15.48		LRIG1_HUMAN (284-453): 4.63e-16: 84: 16.59
+	Mm
		292557 ROBO1_MOUSE (1-350): 3.88e-53: 190: 13.80		SLIT3_MOUSE (13-178): 5.11e-16: 83.9: 17.75
+	Hs
		1166661 LRIG3_HUMAN (6-360): 1.62e-51: 186: 14.60		LRIG1_HUMAN (284-453): 4.63e-16: 84: 16.59
+	Hs
		299584 LRIG2_HUMAN (7-327): 6.22e-53: 190: 15.48		RTN4R_HUMAN (146-262): 6.18e-12: 69.7: 37.29
+	Hs
		1166667 LRIG3_HUMAN (6-360): 1.62e-51: 186: 14.60		LRC4C_HUMAN (349-498): 3.93e-12: 70.9: 17.50
+	Hs
		608113 FGFR4_HUMAN (17-338): 2.95e-51: 184: 17.17		RTN4R_HUMAN (146-262): 6.18e-12: 69.7: 37.29
+	Hs
		296682 ROBO1_HUMAN (84-340): 2.12e-32: 130: 15.59		SLIT2_HUMAN (280-447): 1.19e-19: 95.5: 17.68
+	Dm
		219803 O44924_DROME (5-316): 5.22e-31: 126: 14.55		SLIT_DROME (278-448): 1.32e-20: 98.6: 20.11