HitPredict

Interactor 1: MIER2 (Q8N344)
Mesoderm induction early response protein 2 (Mi-er2)
Gene: MIER2

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 30737378, 21258344
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006338 - chromatin remodeling
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 545
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024