HitPredict

Interactor 1: MIER2 (Q8N344)
Mesoderm induction early response protein 2 (Mi-er2)
Gene: MIER2

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 1273
+	Hs
		1302434 MTA3_HUMAN (128-441): 7.33e-77: 255: 23.01		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		296108 MTA2_HUMAN (117-441): 2.31e-70: 239: 19.84		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1031933 MTA1_HUMAN (143-441): 4.57e-67: 232: 20.71		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		257824 MTA3_HUMAN (128-441): 7.33e-77: 255: 23.01		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257731 MTA2_HUMAN (117-441): 2.31e-70: 239: 19.84		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257777 MTA1_HUMAN (143-441): 4.57e-67: 232: 20.71		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257847 RCOR1_HUMAN (195-471): 5.08e-53: 189: 18.40		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15