HitPredict

Interactor 1: ASCC3 (Q8N3C0)
Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)
Gene: ASCC3

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2202 Hs			1 779
+	Hs
		272278 U520_HUMAN (7-2198): 0: 1584: 37.61		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		272282 U520_HUMAN (7-2198): 0: 1584: 37.61		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90
+	Hs
		1204698 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1271662 DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		571596 DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		787011 MTREX_HUMAN (366-1187): 1.53e-88: 316: 15.84		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		134208 DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1074497 SKI2_HUMAN (445-899): 1.93e-85: 310: 21.98		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		181736 DDX3Y_HUMAN (1252-1734): 5.37e-90: 310: 12.50		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1153276 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1153317 DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		571491 DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1022418 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1133681 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		134083 DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1231289 DDX17_HUMAN (407-898): 4.34e-100: 342: 12.97		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		571517 DDX5_HUMAN (1248-1735): 2.96e-100: 338: 11.38		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		786986 MTREX_HUMAN (366-1187): 1.53e-88: 316: 15.84		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		134122 DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		181718 DDX3Y_HUMAN (1252-1734): 5.37e-90: 310: 12.50		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93