HitPredict

Interactor 1: ASCC3 (Q8N3C0)
Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)
Gene: ASCC3

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2202 Hs			1 400
+	Hs
		272290 U520_HUMAN (7-2198): 0: 1584: 37.61		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1232173 ASCC3_HUMAN (1-2202): 0: 1789: 100.00		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		272207 U520_HUMAN (7-2198): 0: 1584: 37.61		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1204700 DDX42_HUMAN (274-903): 2.66e-98: 343: 13.53		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		787023 MTREX_HUMAN (366-1187): 1.53e-88: 316: 15.84		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1074501 SKI2_HUMAN (445-899): 1.93e-85: 310: 21.98		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		786988 MTREX_HUMAN (366-1187): 1.53e-88: 316: 15.84		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		134124 DDX3X_HUMAN (1252-1734): 3.79e-90: 311: 12.50		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87