HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	20850016, 12700765
Identification Methods	unspecified method, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 560 Hs			1 136
+	Hs
		123231 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		123236 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		123269 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		111555 CBX4_HUMAN (1-560): 7.58e-163: 477: 100.00		K7EK07_HUMAN (1-132): 3.48e-59: 180: 93.18
+	Mm
		223226 CBX4_MOUSE (1-560): 5.82e-156: 459: 88.43		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		935156 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Mm
		675496 CBX2_MOUSE (2-559): 8.06e-91: 290: 22.85		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		952579 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		934768 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1059154 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		952341 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1059165 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Mm
		952770 CBX6_MOUSE (1-419): 2.28e-79: 257: 24.14		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		828230 CBX2_HUMAN (2-559): 1.19e-82: 269: 23.54		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	Hs
		316000 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		316040 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		316012 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		316070 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		316055 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		H37_HUMAN (1-136): 1.11e-58: 179: 94.12
+	Hs
		935387 CDYL_HUMAN (2-288): 4.47e-50: 183: 16.35		H31_HUMAN (1-136): 6.88e-62: 187: 97.06