HitPredict

Interactor 1: SYNPO (Q8N3V7)
Synaptopodin
Gene: SYNPO

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 929 Hs			1 1294
+	Hs
		203261 SYNJ1_HUMAN (599-927): 7.23e-09: 62: 12.57		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Ce
		136791 UNC89_CAEEL (257-851): 3.1e-31: 135: 13.69		HUM6_CAEEL (1-895): 0: 875: 31.42
+	Hs
		1232630 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		724915 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		1232641 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		MYO5B_HUMAN (1016-1294): 4.73e-09: 63.4: 12.41
+	Hs
		1232648 SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00		MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72
+	Hs
		724893 MICA3_HUMAN (231-870): 4.24e-27: 121: 12.97		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		1300994 CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24		MYO5B_HUMAN (1016-1294): 4.73e-09: 63.4: 12.41