HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31478661
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 340
+	Hs
		1330925 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		925630 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		894451 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		951353 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		900924 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		545626 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		436516 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		892604 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Hs
		900348 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		436239 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Mm
		892718 CDC42_MOUSE (1-191): 4.96e-82: 243: 100.00		LIS1_MOUSE (259-340): 1.21e-18: 87.8: 23.17
+	Hs
		436191 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17