HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: ZN546 (Q86UE3)
Zinc finger protein 546 (Zinc finger protein 49)
Gene: ZNF546

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21282530
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 560 Hs			1 836
+	Hs
		316190 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN624_HUMAN (57-830): 0: 1029: 48.46
+	Hs
		983755 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZNF91_HUMAN (147-835): 0: 955: 51.67
+	Hs
		67424 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN850_HUMAN (126-835): 0: 930: 52.95
+	Hs
		64140 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN729_HUMAN (101-814): 0: 907: 46.97
+	Hs
		64135 CBX5_HUMAN (11-171): 7.04e-41: 148: 19.88		ZN729_HUMAN (101-814): 0: 907: 46.97
+	Hs
		316196 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN107_HUMAN (101-781): 0: 843: 47.00
+	Hs
		1027102 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN227_HUMAN (53-831): 0: 892: 41.25
+	Hs
		316135 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN184_HUMAN (326-835): 0: 817: 55.88
+	Hs
		1027217 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN184_HUMAN (326-835): 0: 817: 55.88
+	Hs
		1027294 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN226_HUMAN (102-707): 0: 771: 44.59
+	Hs
		1027126 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN615_HUMAN (313-835): 0: 734: 50.67
+	Hs
		1027123 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN283_HUMAN (393-832): 3.77e-162: 489: 59.77
+	Hs
		1294636 MPP8_HUMAN (6-431): 5.25e-87: 289: 13.72		ZN845_HUMAN (101-356): 4.48e-75: 265: 36.82
+	Hs
		316020 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN33A_HUMAN (498-836): 7.07e-80: 276: 35.57
+	Hs
		316021 CBX6_HUMAN (1-419): 4.68e-61: 209: 24.19		ZN33B_HUMAN (503-836): 1.12e-78: 272: 36.50
+	Hs
		988824 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN33A_HUMAN (498-836): 7.07e-80: 276: 35.57
+	Hs
		1027087 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN571_HUMAN (207-296): 7.39e-21: 99.8: 55.56
+	Hs
		258850 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		Z780A_HUMAN (747-833): 4.3e-19: 94.4: 52.87
+	Hs
		1027211 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN607_HUMAN (736-834): 3.03e-14: 79: 41.41
+	Hs
		1027143 CBX3_HUMAN (9-163): 8.8e-44: 155: 21.94		ZN420_HUMAN (101-206): 3.41e-09: 62.4: 11.11